Results 141 to 150 of about 2,350,890 (295)
Is it time to withdraw from china? [PDF]
This research cross-employs the Social Cognitive Theory (SCT) and three major labor theories comprised of Maslow’s theory, Alderfer’s theory and Herzberg’s theory with Multiple Criteria Decision Making (MCDM) consisting of Factor Analysis (FA ...
Ming-Yuan Hsieh
core
Decision-analytic frameworks for multi-hazard mitigation and adaptation [PDF]
, 2013 Developing effective decision-support for multiple hazards needs to build on a foundation of existing research into best practices for the management of single hazards analysis.
Khazai, B., Komendantova, N., Wenzel, F.
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Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
WHY FUZZY ANALYTIC HIERARCHY PROCESS APPROACH FOR TRANSPORT PROBLEMS? [PDF]
The evaluation of transport projects has become increasingly complex. Different aspects have to be taken into account and the consequences of the problems are usually far reaching and the different policy alternatives are numerous and difficult to ...
Senay Oguztimur
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Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
THE ROLE OF THE UNIVERSITIES IN A REGIONAL INNOVATION SYSTEM – A COMPARATIVE A’WOT - ANALYSIS [PDF]
Universities have an important role in regional innovation systems. In this study, we evaluate and compare two different case regional innovation systems (RIS), one located in the north of Romania, in Bucovina area and the other in Ylä-Savo region, in ...
Carmen Nastase, Miika Kajanus
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Legitimacy analysis of multi-level governance of biodiversity: Evidence from 12 case studies across the EU [PDF]
Legitimacy is regarded as one critical aspect of biodiversity management and nature conservation arrangements. Multi-level governance is claimed to pose several challenges to legitimacy.
Suéskeviécs, Monika
core