Results 71 to 80 of about 777,990 (210)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
IEEE Access, 2018 This paper aims to present a novel outranking approach of the preference ranking organization method for enrichment evaluations (PROMETHEEs) based on Pythagorean fuzzy sets for multiple criteria decision analysis.
Ting-Yu Chen
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
A MapReduce-Based Decision-Making Approach for Multiple Criteria Sorting
SystemsIn the context of big data and artificial intelligence, analyzing and extracting actionable insights from extensive datasets to enhance decision-making processes presents both intriguing opportunities and formidable challenges. Existing multiple criteria
Xiaoxin Mao, Zhanhe Du, Lanlan Zheng
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Technological and Economic Development of Economy, 2013 In this paper, we propose an extension of the standard UTADIS methodology, an approach that originates from multicriteria decision aid (MCDA) for sorting problems, such that it can handle more than one classification criteria simultaneously which ...
Aydin Ulucan, Kazim Baris Atici
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
The Art of Supporting Decision-Making
Exchanges, 2017 The provision of decision support methods and strategies is of primary importance to guarantee justifiable decision-making processes. Many of the experts and practitioners in this area gathered from 3 to 7 August 2015 at the 23rd Conference of the ...
Marco Cinelli
doaj
MATEC Web of Conferences, 2018 Nowadays modern monolithic construction is moving toward in balanced structural safety improving, energy efficiency and cost reduction with no-loss in quality characteristics.
Korol Elena +2 more
doaj +1 more source