Results 81 to 90 of about 29,087,711 (292)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
A MapReduce-Based Decision-Making Approach for Multiple Criteria Sorting
SystemsIn the context of big data and artificial intelligence, analyzing and extracting actionable insights from extensive datasets to enhance decision-making processes presents both intriguing opportunities and formidable challenges. Existing multiple criteria
Xiaoxin Mao, Zhanhe Du, Lanlan Zheng
doaj +1 more source
IEEE Access, 2018 This paper aims to present a novel outranking approach of the preference ranking organization method for enrichment evaluations (PROMETHEEs) based on Pythagorean fuzzy sets for multiple criteria decision analysis.
Ting-Yu Chen
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Technological and Economic Development of Economy, 2013 In this paper, we propose an extension of the standard UTADIS methodology, an approach that originates from multicriteria decision aid (MCDA) for sorting problems, such that it can handle more than one classification criteria simultaneously which ...
Aydin Ulucan, Kazim Baris Atici
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
On Combining Explainable Artificial Intelligence and Interactive Multiobjective Optimization in Data-Driven Decision Support [PDF]
, 2019 nonPeerReviewe
Äyrämö, Sami +3 more
core +1 more source
The Art of Supporting Decision-Making
Exchanges, 2017 The provision of decision support methods and strategies is of primary importance to guarantee justifiable decision-making processes. Many of the experts and practitioners in this area gathered from 3 to 7 August 2015 at the 23rd Conference of the ...
Marco Cinelli
doaj
MATEC Web of Conferences, 2018 Nowadays modern monolithic construction is moving toward in balanced structural safety improving, energy efficiency and cost reduction with no-loss in quality characteristics.
Korol Elena +2 more
doaj +1 more source