Results 131 to 140 of about 65,584 (272)

Optimizing Maternal Microbiome: Role in Improved Conception and Pregnancy Outcome

open access: yesReproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
Maternal microbiome optimization: Minimized risk and simple corrective steps. ABSTRACT Purpose To evaluate the role of optimizing the maternal microbiome in improving pregnancy outcomes, focusing on preconception and early gestation, and to propose practical diagnostic and preventive strategies, particularly in low‐ and middle‐income countries (LMIC ...
Eytan R. Barnea   +7 more
wiley   +1 more source

Graded Calorie Restriction Causes Graded Slowing of Epigenetic Ageing in Mice

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
Graded calorie restriction in male mice modified epigenetic signatures of the liver and slowed ageing rate in a graded manner. ABSTRACT DNA methylation variation is associated with chronological ageing. Calorie restriction (CR) prolongs lifespan and healthspan in many species.
Timothy P. Moulds   +6 more
wiley   +1 more source

Spatial transcriptomics mapping of immune cell and TGFβ signalling pathway heterogeneity in testicular germ cell tumours

open access: yesAndrology, Volume 14, Issue 1, Page 210-227, January 2026.
Abstract Background Testicular germ cell tumours (TGCTs) are amongst the most common malignancies in young men, and their incidence is increasing worldwide. Tissue heterogeneity hampers efforts to understand how TGCT precursors (termed germ cell neoplasia in situ; GCNIS) emerge and progress, restricting elucidation of new strategies for diagnosis and ...
Sarah C. Moody   +6 more
wiley   +1 more source

Precursor Lesions in Patients With Multiple Endocrine Neoplasia Type 1--Associated Duodenal Gastrinomas [PDF]

open access: bronze, 2005
Martin Anlauf   +9 more
openalex   +1 more source

A Combinatorial Effect of Immune Checkpoint Inhibitors and CD40 Agonistic Antibody in Murine Pancreatic Cancer Model

open access: yesCancer Science, Volume 117, Issue 1, Page 8-18, January 2026.
We established and extensively analyzed an organoid‐based mouse model that closely mimics human pancreatic ductal adenocarcinoma. Monotherapy with an immune checkpoint inhibitor cocktail or a CD40 agonist antibody showed minimal efficacy. However, combining both reagents produced a strong synergistic effect by enhancing anti‐tumor immunity.
Juri Ichikawa   +12 more
wiley   +1 more source

Bone disorders in type 1 multiple endocrine neoplasia syndrome: A review of clinical data

open access: diamond, 2021
А. М. Горбачева   +2 more
openalex   +2 more sources

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