Optimizing Maternal Microbiome: Role in Improved Conception and Pregnancy Outcome
Maternal microbiome optimization: Minimized risk and simple corrective steps. ABSTRACT Purpose To evaluate the role of optimizing the maternal microbiome in improving pregnancy outcomes, focusing on preconception and early gestation, and to propose practical diagnostic and preventive strategies, particularly in low‐ and middle‐income countries (LMIC ...
Eytan R. Barnea +7 more
wiley +1 more source
A novel <i>MEN1</i> mutation in a Japanese adolescent with multiple endocrine neoplasia type 1
Masatsune Itoh, Yutaka Saikawa
openalex +2 more sources
Limited Role of Meta-iodobenzylguanidine Scintigraphy in Imaging Phaeochromocytoma in Patients with Multiple Endocrine Neoplasia Type II [PDF]
R. P. F. Dullaart J. S. de Graaf
openalex +1 more source
Graded Calorie Restriction Causes Graded Slowing of Epigenetic Ageing in Mice
Graded calorie restriction in male mice modified epigenetic signatures of the liver and slowed ageing rate in a graded manner. ABSTRACT DNA methylation variation is associated with chronological ageing. Calorie restriction (CR) prolongs lifespan and healthspan in many species.
Timothy P. Moulds +6 more
wiley +1 more source
Questions and Controversies About Parathyroid Pathophysiology in Children With Multiple Endocrine Neoplasia Type 1 [PDF]
Stephen J. Marx, Delmar Muniz Lourenço
openalex +1 more source
Abstract Background Testicular germ cell tumours (TGCTs) are amongst the most common malignancies in young men, and their incidence is increasing worldwide. Tissue heterogeneity hampers efforts to understand how TGCT precursors (termed germ cell neoplasia in situ; GCNIS) emerge and progress, restricting elucidation of new strategies for diagnosis and ...
Sarah C. Moody +6 more
wiley +1 more source
Precursor Lesions in Patients With Multiple Endocrine Neoplasia Type 1--Associated Duodenal Gastrinomas [PDF]
Martin Anlauf +9 more
openalex +1 more source
We established and extensively analyzed an organoid‐based mouse model that closely mimics human pancreatic ductal adenocarcinoma. Monotherapy with an immune checkpoint inhibitor cocktail or a CD40 agonist antibody showed minimal efficacy. However, combining both reagents produced a strong synergistic effect by enhancing anti‐tumor immunity.
Juri Ichikawa +12 more
wiley +1 more source
Molecular and Genetic Mechanisms of Tumorigenesis in Multiple Endocrine Neoplasia Type-1 [PDF]
Sydney S. Guo, Mark Sawicki
openalex +1 more source
Bone disorders in type 1 multiple endocrine neoplasia syndrome: A review of clinical data
А. М. Горбачева +2 more
openalex +2 more sources

