Results 11 to 20 of about 26,682 (180)
The Oncologist, EarlyView., 2021 Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth +10 more
wiley +1 more source
Multiple endocrine neoplasia type 1
Indian Journal of Endocrinology and Metabolism, 2012 Multiple endocrine neoplasia type 1 (MEN1) is characterized by the occurrence of parathyroid, pancreatic islet and anterior pituitary tumors. Some patients may also develop carcinoid tumors, adrenocortical tumors, facial angiofibromas, collagenomas, and ...
R V Thakker
doaj +1 more source
Multiple endocrine neoplasia type 2A
Kaohsiung Journal of Medical Sciences, 2012 Multiple endocrine neoplasia type 2A (MEN 2A) is an autosomal dominant inherited cancer syndrome that expresses nonendocrine and endocrine tumors.
Chiung-Tang Huang +2 more
doaj +1 more source
Multiple endocrine neoplasia type 2
Orphanet Journal of Rare Diseases, 2006 Multiple Endocrine Neoplasia Type 2 (MEN2) is a rare hereditary complex disorder characterized by the presence of medullary thyroid carcinoma (MTC), unilateral or bilateral pheochromocytoma (PHEO) and other hyperplasia and/or neoplasia of different ...
Luzi Ettore +6 more
doaj +1 more source
Endocrinology Research and Practice, 2023 Objective: This study aims to evaluate the presence of multiple endocrine neoplasia-1 mutations in patients with primary hyperparathyroidism detected on clinical and sonographical suspicion.
Muhammet Cüneyt Bilginer +7 more
doaj
Over-representation of the G12S polymorphism of the SDHD gene in patients with MEN2A syndrome
Clinics, 2012 OBJECTIVE: To evaluate whether germline variants of the succinate dehydrogenase genes might be phenotypic modifiers in patients with multiple endocrine neoplasia type 2.
Nikoletta Lendvai +10 more
doaj +1 more source
Multiple endocrine neoplasia 1: a broad overview
Therapeutic Advances in Chronic Disease, 2021 This review article discusses the diagnoses and treatment of patients with multiple endocrine neoplasia type 1 (MEN 1). The most common tumors associated with MEN 1 are located in the pancreas, pituitary, and parathyroid glands.
Rachel Thompson, Christine S. Landry
doaj +1 more source
Genotype-phenotype correlation in multiple endocrine neoplasia type 2
Clinics, 2012 Multiple endocrine neoplasia type 2 is an autosomal-dominant hereditary cancer syndrome caused by missense gain-of-function mutations of the rearranged during transfection proto-oncogene, which encodes the receptor tyrosine kinase, on chromosome 10.
Friedhelm Raue, Karin Frank-Raue
doaj +1 more source
Multiple endocrine neoplasia: the Chilean experience
Clinics, 2012 Multiple endocrine neoplasia (MEN) types 1 and 2 are genetic diseases that are inherited as autosomal traits. The major clinical manifestations of multiple endocrine neoplasia type 1 include the so-called "3 P's": parathyroid, pituitary, and pancreatic ...
René E. Diaz, Nelson Wohllk
doaj +1 more source
Surgical treatment of pancreatic endocrine tumors in multiple endocrine neoplasia type 1
ClinicsSurgical approaches to pancreatic endocrine tumors associated with multiple endocrine neoplasia type 1 may differ greatly from those applied to sporadic pancreatic endocrine tumors.
Marcel Cerqueira Cesar Machado
doaj +1 more source