Results 1 to 10 of about 38,029,237 (226)

Multiple endocrine neoplasia type 1

Indian Journal of Endocrinology and Metabolism, 2012
Multiple endocrine neoplasia type 1 (MEN1) is characterized by the occurrence of parathyroid, pancreatic islet and anterior pituitary tumors. Some patients may also develop carcinoid tumors, adrenocortical tumors, facial angiofibromas, collagenomas, and ...
R V Thakker
doaj   +10 more sources

Multiple endocrine neoplasia type 1 [PDF]

Orphanet Journal of Rare Diseases, 2006
Multiple Endocrine Neoplasia type 1 (MEN1) is a rare autosomal dominant hereditary cancer syndrome presented mostly by tumours of the parathyroids, endocrine pancreas and anterior pituitary, and characterised by a very high penetrance and an equal sex ...
Luzi Ettore, Gozzini Alessia, Sala Silvia, Monte Francesca, Falchetti Alberto, Marini Francesca, Brandi Maria   +6 more
doaj   +7 more sources

Multiple Endocrine Neoplasia Type 1. [PDF]

Dtsch Arztebl Int
Multiple endocrine neoplasia type 1 (MEN1) is a rare genetic disease of autosomal dominant inheritance, with an estimated prevalence of 3-20/100 000. Its main feature is neuroendocrine neoplasia in the parathyroid glands, the endocrine pancreas, the duodenum, and the pituitary gland. In this article, we review the diagnostic and therapeutic options for
Manoharan J, Albers MB, Rinke A, Adelmeyer J, Görlach J, Bartsch DK.   +5 more
europepmc   +5 more sources

Gastrinoma in Multiple Endocrine Neoplasia Type 1 [PDF]

Acta Oncológica, 1991
Extensive experience from patients with gastrinoma as part of the multiple endocrine neoplasia type 1 (MEN 1) syndrome has revealed that MEN 1-gastrinoma patients show important differences from patients with sporadic gastrinoma. These differences comprise clinical, pathological and biochemical features, but are especially pertinent to the therapeutic ...
C B Lamers
exaly   +3 more sources

18F-FDOPA PET/CT for neuroendocrine tumors in multiple endocrine neoplasia type 1 [PDF]

Frontiers in Endocrinology
ObjectiveThe aim of this study was to evaluate the efficacy of 6-18F-fluoro-L-3,4-dihydroxyphenylalanine (18F-FDOPA) positron emission tomography/computed tomography (PET/CT) in the identification of primary and metastatic NETs in patients with multiple ...
Aisha A. Tepede, Maya Lee, James Welch, Adel Mandl, Craig Cochran, Ahmed Hamimi, Lee S. Weinstein, William F. Simonds, Ahmed M. Gharib, Corina Millo, Samira M. Sadowski, Jenny E. Blau, Smita Jha   +12 more
doaj   +2 more sources

Genotype-phenotype correlation in multiple endocrine neoplasia type 1 [PDF]

JCI Insight
BACKGROUND Among patients with multiple endocrine neoplasia type 1 (MEN1), 80% develop duodenopancreatic neuroendocrine tumors (dpNETs), of whom 15%–25% die of metastasis. There is a need to identify biomarkers to predict aggressive disease.
Charlita C. Worthy, Rana Tora, Chandra N. Uttarkar, James M. Welch, Lynn Bliss, Craig Cochran, Anisha Ninan, Sheila Kumar, Stephen Wank, Sungyoung Auh, Lee S. Weinstein, William F. Simonds, Sunita K. Agarwal, Jenny E. Blau, Smita Jha   +14 more
doaj   +2 more sources

Extra-adrenal adrenocortical cancer associated with multiple endocrine neoplasia type 1 [PDF]

Endocrinology, Diabetes & Metabolism Case Reports
Adrenocortical carcinoma (ACC) is a rare malignant tumour arising from the adrenal cortex, with an estimated annual incidence of one to two patients per million. Ectopic ACCs are extremely rare.
Deirdre Green, Kate Richards, Brendan Doyle, Chris Thompson, Arnold Hill, Michael W O’Reilly, Mark Sherlock   +6 more
doaj   +2 more sources

Multiple endocrine neoplasia type 1 with neuroglycopenic symptoms with a novel heterozygous MEN1 gene mutation [PDF]

World Journal of Surgical Oncology
Background Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder caused by mutations in the MEN1 gene located on the long arm of chromosome 11. Case presentation.
Xinchen Jiang, Shixiong Tang, Guoqing Yang, Lite Ge, Fan Peng   +4 more
doaj   +2 more sources

Multiple endocrine neoplasia type 1 in childhood and description of a novel variant [PDF]

Revista Paulista de Pediatria
Objective To describe a case of multiple endocrine neoplasia type 1 in the pediatric age group and its molecular diagnosis. Case description: An 11-year-old boy began to present generalized tonic-clonic seizures in the presence of hypoglycemia, with ...
Mayara Teixeira Alexandrino Sales, Rebeca Costa Castelo Branco, Carlos Henrique Paiva Granjeiro, Milena Silva Sousa, Luciana Felipe Férrer Aragão, Annelise Barreto de Carvalho, Ana Paula Dias Rangel Montenegro, Ana Rosa Pinto Quidute   +7 more
doaj   +2 more sources

Genetic Landscape and Clinical Manifestations of Multiple Endocrine Neoplasia Type 1 in a Korean Cohort: A Multicenter Retrospective Analysis [PDF]

Endocrinology and Metabolism
Background Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterized by tumors in multiple endocrine organs, caused by variants in the MEN1 gene.
Boram Kim, Seung Hun Lee, Chang Ho Ahn, Han Na Jang, Sung Im Cho, Jee-Soo Lee, Yu-Mi Lee, Su-Jin Kim, Tae-Yon Sung, Kyu Eun Lee, Woochang Lee, Jung-Min Koh, Moon-Woo Seong, Jung Hee Kim   +13 more
doaj   +2 more sources