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Surgical treatment of pancreatic endocrine tumors in multiple endocrine neoplasia type 1 [PDF]
Surgical approaches to pancreatic endocrine tumors associated with multiple endocrine neoplasia type 1 may differ greatly from those applied to sporadic pancreatic endocrine tumors.
Marcel Cerqueira Cesar Machado
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Clinical case: multiple endocrine neoplasia type 1 (MEN 1) [PDF]
Multiple endocrine neoplasia syndrome type 1 (MEN1, Wermer syndrome) – group o а heterogeneous inherited deseases, caused by hyperlasia or neoplasia of several endocrine glands.
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Multiple endocrine neoplasia type 1 [PDF]
AbstractMultiple endocrine neoplasia‐1 (MEN‐1) is an autosomal dominant inherited syndrome that occurs due to inactivating mutations of the MEN1 gene locus, coding for a tumor‐suppressor protein, menin. The components of MEN‐1 are hyperparathyroidism due to multiple parathyroid adenomas, pancreatic neuroendocrine tumors, and pituitary adenomas, in ...
Doherty, Gerard M.
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Multiple endocrine neoplasia type 1 (MEN1) [PDF]
Multiple Endocrine Neoplasia type 1 (MEN1) is an autosomal-dominant disorder characterised by the occurrence of tumours of the parathyroids, pancreas and anterior pituitary. The MEN1 gene, consists of 10 exons that encode a 610-amino acid protein referred to as Menin. Menin is predominantly a nuclear protein that has roles in transcriptional regulation,
A Calender, Calender, A
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Multiple endocrine neoplasia: the Chilean experience
Multiple endocrine neoplasia (MEN) types 1 and 2 are genetic diseases that are inherited as autosomal traits. The major clinical manifestations of multiple endocrine neoplasia type 1 include the so-called "3 P's": parathyroid, pituitary, and pancreatic ...
René E. Diaz, Nelson Wohllk
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Multiple endocrine neoplasia type 1.
Abstract Combined clinical and laboratory investigations of multiple endocrine neoplasia type 1 (MEN1) have resulted in an increased understanding of this disorder which may be inherited as an autosomal dominant condition. Defining the features of each disease manifestation in MEN1 has improved patient management and treatment, and ...
Pannett, A, Thakker, R
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Multimodality appearance of multiple endocrine neoplasia type 1: A case report
Multiple endocrine neoplasia type 1 is a rare autosomal dominant disorder classically characterized by a predisposition to tumors of the parathyroid glands, anterior pituitary, and enteropancreatic endocrine cells.
John Monge, MD +2 more
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Fast-growing pancreatic neuroendocrine carcinoma in a patient with multiple endocrine neoplasia type 1: a case report [PDF]
Introduction Predictive genetic screening and regular screening programs in patients with multiple endocrine neoplasia type 1 are intended to detect and treat malignant tumors at the earliest stage possible. Malignant neuroendocrine pancreatic tumors are
Waldmann Jens +6 more
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Usually, primary hyperparathyroidism is the first endocrinopathy to be diagnosed in patients with multiple endocrine neoplasia type 1, and is also the most common one.
Francesco Tonelli +3 more
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PDP type brain tumor in association with multiple endocrine neoplasia type 1 [PDF]
Multiple endocrine neoplasia type 1 (MEN1) is a rare autosomal dominant syndrome caused by inactivating pathogenic variants in the tumor suppressor gene menin 1 on chromosome 11q13 (Falchetti et al., 2009).
Halldór Bjarki Einarsson +9 more
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