Results 41 to 50 of about 676,606 (300)

Experimental Investigation on the Post-Peak Short-Term and Creep Behavior of Fractured Sandstone

Energies, 2020
Short-term and creep tests of fractured sandstone with different degrees of damage prepared using pre-peak and post-peak unloading tests on intact sandstone were carried out using a servo-controlled rock mechanics system.
Yijiang Zong, Lijun Han, Yuhao Jin, Weisheng Zhao, Lingdong Meng   +4 more
doaj   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Study on main failure modes of multiple-holes structures based on branch-bound method

Xibei Gongye Daxue Xuebao, 2022
Aiming at the typical five-hole structure on the aircraft skin, combined with the failure criterion of multi crack structure and considering the random factors affecting the residual life distribution of multiple crack structure, this paper applies the ...
XIE Wei, ZHANG Yadan, MA Zehua, FENG Jinrong, WU Yu   +4 more
doaj   +1 more source

Optimal Inspection and Replacement Decisions for Multiple Failure Modes [PDF]

, 2004
Cost functions, associated with the gamma process for modelling deterioration, are extended to include multiple failure modes. The application of these cost functions is demonstrated by an example in the process industry. We consider an elbow in a pipeline, which is susceptible to thinning due to corrosion and stress corrosion cracking.
Maarten-Jan Kallen, Jan M. van Noortwijk
openaire   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Promoting sustainable water distribution networks: Modeling of water pipe failure factors and modes

Cleaner Engineering and Technology
Water pipe failure significantly undermines the sustainability and resilience of water distribution networks (WDNs), leading to substantial environmental, economic, and social impacts.
Ridwan Taiwo, Tarek Zayed, Nehal Elshaboury, Ghasan Alfalah, Eslam Mohammed Abdelkader   +4 more
doaj   +1 more source

Reliability-Based Robust Design of Mechanical Components with Correlated Failure Modes Based on Moment Method

Advances in Mechanical Engineering, 2014
There are usually several potential failure modes in mechanical components. The conventional model for the system analysis is built under the condition that all failure modes are independent of each other.
Hao Lu, Yonghui He, Yimin Zhang
doaj   +1 more source