Results 41 to 50 of about 948,028 (287)

Non-genomic effects of PPARgamma ligands: inhibition of GPVI-stimulated platelet activation [PDF]

, 2010
BACKGROUND: Peroxisome proliferator-activated receptor-(gamma) (PPAR(gamma)) is expressed in human platelets although in the absence of genomic regulation in these cells, its functions are unclear.
Akbiyik, Ali, Ali, Asselin, Beckman, Chapelsky, Chinetti, Cicmil, Cicmil, Croxtall, Dayuan, Dormandy, Falati, Gibbins, Gibbins, Gibbins, Gross, Hsueh, Hubbard, Irons, Jones, Jones, Khanolkar, Lago, Lehmann, Lipscombe, Losel, Malaver, McGuire, Moraes, Moraes, Moraes, Moro, Nieswandt, Nieuwenhuis, Nissen, O’Brien, Patil, Poole, Randriamboavonjy, Sauer, Smith, Tucker, Weyrich   +43 more
core   +2 more sources

Presenilin/γ-secretase and inflammation

Frontiers in Aging Neuroscience, 2010
Presenilins (PS) are the catalytic components of γ-secretase, an aspartyl protease that regulates through proteolytic processing the function of multiple signaling proteins.
Carlos A Saura
doaj   +1 more source

Alternating sign multibump solutions of nonlinear elliptic equations in expanding tubular domains

, 2012
Let $\Gamma$ denote a smooth simple curve in $\mathbb{R}^{N}$, $N\geq2$, possibly with boundary. Let $\Omega_{R}$ be the open normal tubular neighborhood of radius 1 of the expanded curve $R\Gamma:=\{Rx\mid x\in \Gamma\smallsetminus\partial\Gamma ...
Ackermann, Nils, Clapp, Monica, Pacella, Filomena   +2 more
core   +1 more source

Statistics of α - μ random variables and their applications in wireless multihop relaying and multiple scattering channels [PDF]

, 2015
Exact results for the probability density function (PDF) and cumulative distribution function (CDF) of the sum of ratios of products (SRP) and the sum of products (SP) of independent α-μ random variables (RVs) are derived.
Alouini, Mohamed-Slim, Chen, Yunfei, Wang, Kezhi, Wang, Tian   +3 more
core   +1 more source

Modules in the photoreceptor RGS9-1•Gβ5L GTPase-accelerating protein complex control effector coupling, GTPase acceleration, protein folding, and stability [PDF]

, 2000
RGS (regulators of G protein signaling proteins regulate G protein signaling by accelerating GTP hydrolysis, but little is known about regulation of GTPase-accelerating protein (GAP) activities or roles of domains and subunits outside the catalytic cores.
Chen, Ching-Kang, El-Hodiri, Heithem M., He, Wei, Jamrich, Milan, Lu, Lisha, Simon, Melvin I., Slep, Kevin C., Wensel, Theodore G., Zhang, Xue   +8 more
core   +1 more source

Empowering the Future of Hybrid MIMO-RF UOWC: Advanced Statistical Framework for Channel Modeling and Optimization for the Post-5G Era and Beyond

IEEE Access, 2023
This research work examines the reliability of a wireless communication system that uses a hybrid radio frequency (RF) and underwater optical wireless communication (UOWC) in a dual-hop system.
Latif Jan, Ghassan Husnain, Waleed Tariq Sethi, Ihtisham Ul Haq, Yazeed Yasin Ghadi, Hend Khalid Alkahtani   +5 more
doaj   +1 more source

Milnor-Selberg zeta functions and zeta regularizations

, 2011
By a similar idea for the construction of Milnor's gamma functions, we introduce "higher depth determinants" of the Laplacian on a compact Riemann surface of genus greater than one.
Adamchik, Barnes, Barnes, Berndt, Bump, Deninger, D’Hoker, Eichler, Erdélyi, Ibukiyama, Keating, Kubert, Kurokawa, Kurokawa, Kurokawa, Masato Wakayama, Milnor, Nobushige Kurokawa, Rosenberg, Sarnak, Srivastava, Vignéras, Voros, Wakayama, Yoshinori Yamasaki   +24 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Non-dispersive and weakly dispersive single-layer flow over an axisymmetric obstacle: the equivalent aerofoil formulation [PDF]

, 2007
Non-dispersive and weakly dispersive single-layer flows over axisymmetric obstacles, of non-dimensional height M measured relative to the layer depth, are investigated. The case of transcritical flow, for which the Froude number F of the oncoming flow is
Esler, JG, Johnson, ER, Rump, OJ
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source