Results 61 to 70 of about 945,067 (284)

Defining New Multiple $$\log \Gamma $$ -Type Functions

, 2022
AbstractIn the previous chapter, we tested our results on some multiple $$\log \Gamma $$ log Γ -type functions that are well-known special functions. It is clear, however, that there are many other multiple $$\log \Gamma $$ log Γ -type functions that are ...
Jean-Luc Marichal, Naïm Zenaïdi
openaire   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Derivatives of Multiple $$\log \Gamma $$ -Type Functions

, 2022
AbstractIn this chapter, we discuss the higher order differentiability properties of Σg when g lies in $$\mathcal {C}^r\cap \mathcal {D}^p\cap \mathcal {K}^{\max \{p,r\}}$$ C r ∩
Jean-Luc Marichal, Naïm Zenaïdi
openaire   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Dualities for absolute zeta functions and multiple gamma functions

Proceedings of the Japan Academy, Series A, Mathematical Sciences, 2013
We study absolute zeta functions from the view point of a canonical normalization. We introduce the absolute Hurwitz zeta function for the normalization. In particular, we show that the theory of multiple gamma and sine functions gives good normalizations in cases related to the Kurokawa tensor product.
Kurokawa, Nobushige, Ochiai, Hiroyuki
openaire   +3 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

On Barnes' Multiple Zeta and Gamma Functions

Advances in Mathematics, 2000
In this paper the author presents new frameworks for studying Barnes' multiple zeta and gamma functions. Barnes' multiple zeta function defined as \[ \zeta_{N}(s, w |a_{1}, \ldots, a_{N}) \quad = \sum_{m_{1}, \ldots, m_{N} = 0}^{\infty} (w+m_{1}a_{1}+ \cdots + m_{N}a_{N})^{-s}, \] \[ \operatorname {Re} w > 0, \;\operatorname {Re} s > N,\;a_{i}>0 \quad (
openaire   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Multiple cross-frequency coupling analysis of resting-state EEG in patients with mild cognitive impairment and Alzheimer’s disease

Frontiers in Aging Neuroscience, 2023
IntroductionElectroencephalographic (EEG) abnormalities are seen in patients with Alzheimer’s disease (AD) and mild cognitive impairment (MCI) with characteristic features of cognitive impairment.
Xi Chen, Yingjie Li, Yingjie Li, Renren Li, Xiao Yuan, Meng Liu, Meng Liu, Wei Zhang, Yunxia Li, Yunxia Li   +9 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source