Results 71 to 80 of about 948,028 (287)

Evaluating Oilseed Biofuel Production Feasibility in California’s San Joaquin Valley Using Geophysical and Remote Sensing Techniques

Sensors, 2017
Though more costly than petroleum-based fuels and a minor component of overall military fuel sources, biofuels are nonetheless strategically valuable to the military because of intentional reliance on multiple, reliable, secure fuel sources.
Dennis L. Corwin, Kevin Yemoto, Wes Clary, Gary Banuelos, Todd H. Skaggs, Scott M. Lesch, Elia Scudiero   +6 more
doaj   +1 more source

Euler and the multiplication formula for the Gamma Function

Euleriana, 2021
We show that an apparently overlooked result of Euler from \cite{E421} is essentially equivalent to the general multiplication formula for the $ $-function that was proven by Gauss in \cite{Ga28}.
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Gene expression profiling in cells with enhanced gamma-secretase activity.

PLoS ONE, 2009
BackgroundProcessing by gamma-secretase of many type-I membrane protein substrates triggers signaling cascades by releasing intracellular domains (ICDs) that, following nuclear translocation, modulate the transcription of different genes regulating a ...
Alexandra I Magold, Matthias Cacquevel, Patrick C Fraering   +2 more
doaj   +1 more source

Shifted phase of EEG cross-frequency coupling in individuals with Phelan-McDermid syndrome

Molecular Autism, 2021
Background Phelan-McDermid Syndrome (PMS) is a rare condition caused by deletion or mutation of the SHANK3 gene. Individuals with PMS frequently present with intellectual disability, autism spectrum disorder, and other neurodevelopmental challenges ...
Michael. G. Mariscal, Elizabeth Berry-Kravis, Joseph D. Buxbaum, Lauren E. Ethridge, Rajna Filip-Dhima, Jennifer H. Foss-Feig, Alexander Kolevzon, Meera. E. Modi, Matthew W. Mosconi, Charles A. Nelson, Craig M. Powell, Paige M. Siper, Latha Soorya, Andrew Thaliath, Audrey Thurm, Bo Zhang, Mustafa Sahin, April R. Levin, the Developmental Synaptopathies Consortium   +18 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

A note on the singular Sturm-Liouville problem with infinitely many solutions

Electronic Journal of Differential Equations, 2002
We consider the Sturm-Liouville nonlinear boundary-value problem $$ displaylines{ -u''(t) = a(t)f(u(t)), quad 0 < t < 1, cr alpha u(0) - eta u'(0) =0, quad gamma u(1) + delta u'(1) = 0, } $$ where $alpha$, $eta$, $gamma$, $delta geq 0$, $alpha gamma ...
Nickolai Kosmatov
doaj  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Multiple sine, multiple elliptic gamma functions and rational cones

, 2014
We define generalizations of the multiple elliptic gamma functions and the multiple sine functions, labelled by rational cones in $\mathbb{R}^r$. For $r=2,3$ we prove that the generalized multiple elliptic gamma functions enjoy a modular property determined by the cone.
Tizzano, Luigi, Winding, Jacob
openaire   +2 more sources