Results 51 to 60 of about 10,596 (181)

Abstract Supplement

open access: yesPulmonary Medicine, Volume 2026, Issue 1, 2026.

Marzia Folegani, Semonti Nandi
wiley   +1 more source

Evaluation and selection of tandem repeat loci for Streptococcus pneumoniae MLVA strain typing

open access: yesBMC Microbiology, 2005
Background Precise identification of bacterial pathogens at the strain level is essential for epidemiological purposes. In Streptococcus pneumoniae, the existence of 90 different serotypes makes the typing particularly difficult and requires the use of ...
Valjevac Samina   +7 more
doaj   +1 more source

Francisella tularensis strain typing using multiple-locus, variable-number tandem repeat analysis [PDF]

open access: yes, 2001
Francisella tularensis, the etiological agent of tularemia, is found throughout the Northern hemisphere. After analyzing the F. tularensis genomic sequence for potential variable-number tandem repeats (VNTRs), we developed a multilocus VNTR analysis ...
Abrams, Michelle   +5 more
core   +2 more sources

Integrated phenotypic and proteomic screening identifies top‐tier Alzheimer's disease therapeutic targets

open access: yesAlzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract INTRODUCTION Alzheimer's disease (AD) is a complex neurodegenerative disorder. Hundreds of therapeutic targets have been nominated through genetic and multi‐omic studies, but effective prioritization remains a major bottleneck. METHODS We applied an integrative screening framework to assess 29 candidate targets from risk‐enriched biological ...
Gregory A. Cary   +12 more
wiley   +1 more source

Molecular Characterization of Shigella sonnei: An Increasingly Prevalent Etiologic Agent of Shigellosis in Guizhou Province, Southwest of China.

open access: yesPLoS ONE, 2016
BackgroundShigellosis is a serious problem in Guizhou and Shigella sonnei is an increasingly prevalent etiologic agent of local shigellosis cases. No data, however, are available about the molecular characterization of the local isolates of S. sonnei. We
Shijun Li   +10 more
doaj   +1 more source

Impact of diversity of Mycoplasma hyopneumoniae strains on lung lesions in slaughter pigs [PDF]

open access: yes, 2017
The importance of diversity of Mycoplasma hyopneumoniae (M. hyopneumoniae) strains is not yet fully known. This study investigated the genetic diversity of M.
Arsenakis, Ioannis   +7 more
core   +2 more sources

High throughput multiple locus variable number of tandem repeat analysis (MLVA) of Staphylococcus aureus from human, animal and food sources.

open access: yesPLoS ONE, 2012
Staphylococcus aureus is a major human pathogen, a relevant pathogen in veterinary medicine, and a major cause of food poisoning. Epidemiological investigation tools are needed to establish surveillance of S.
Daniel Sobral   +11 more
doaj   +1 more source

MLVA based classification of Mycobacterium tuberculosis complex lineages for a robust phylogeographic snapshot of its worldwide molecular diversity. [PDF]

open access: yesPLoS ONE, 2012
Multiple-locus variable-number tandem repeat analysis (MLVA) is useful to establish transmission routes and sources of infections for various microorganisms including Mycobacterium tuberculosis complex (MTC).
Véronique Hill   +6 more
doaj   +1 more source

Sex as a modifier of genetic risk for type 1 diabetes

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue 12, Page 6857-6868, December 2025.
Abstract Sex differences influence the pathogenesis of type 1 diabetes (T1D), yet most genetic studies have treated sex as a control covariate rather than a dynamic effect modifier. Sex influences immune cell behaviour, including CD4+ and CD8+ T cell activation, regulatory T cell stability, B cell autoantibody production, dendritic cell priming and ...
Hui‐Qi Qu, Hakon Hakonarson
wiley   +1 more source

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