Results 61 to 70 of about 10,596 (181)

A Study on molecular characterization of Razi Bacillus anthracis Sterne 34F2 substrain in Iran

Archives of Razi Institute, 2016
Anthrax, a zoonotic disease caused by Bacillus anthracis, has affected humans since ancient times. For genomic characterization of Razi B. anthracis Sterne 34F2 substrain, single nucleotide polymorphism (SNP) genotyping method developed by Van Erth ...
Tadayon, K., Moazeni Jula, G., Banihashemi, R.,, Sekhavati, M., Naseri Rad, Razaz, H.   +5 more
doaj  

Phenotypic and genotypic characterization of Brucella abortus biovar 4 isolates from cattle in Brazil

Ciência Rural, 2022
: The aim of the present study was to characterize (phenotypically and genotypically) two strains of Brucella abortus identified as belonging to biovar 4 isolated from cattle in Brazil.
Rafaella Silva Andrade, Carine Rodrigues Pereira, Paulo Martins Soares Filho, Patrícia Gomes de Souza, Antônio Augusto Fonseca Júnior, Silvia Minharro, Marisa da Costa, Elaine Maria Seles Dorneles, Andrey Pereira Lage   +8 more
doaj   +1 more source

Long‐read sequencing reveals genomic and epigenomic variation in the dark genome of human Alzheimer's disease

Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract INTRODUCTION Faulty DNA repair and epigenetic regulation contribute to neurodegeneration in Alzheimer's disease. Long‐read sequencing enables analysis of “dark regions” that are difficult to study via traditional sequencing methodologies.
Paulino Ramirez, Wenyan Sun, Shiva Kazempour Dehkordi, Habil Zare, Giovanni Pascarella, Piero Carninci, Bernard Fongang, Kevin F. Bieniek, Bess Frost   +8 more
wiley   +1 more source

Molecular and genetic analysis of Mycobacterium tuberculosis population in the Vologda Region with low tuberculosis incidence

Инфекция и иммунитет, 2021
The Vologda Region is characterized by a relatively calm epidemic situation for tuberculosis in Russia: the incidence rate in 2010—2018 is decreased from 45.2 to 15.8 per 100 thousand of the population (44.4 in Russia).
А. A. Vyazovaya, I. A. Lebedeva, N. B. Ushakova, V. V. Pavlov, A. A. Gerasimova, N. S. Solovieva, V. Yu. Zhuravlev, O. V. Narvskaya   +7 more
doaj   +1 more source

Human Endogenous Retroviruses and Diseases

MedComm, Volume 6, Issue 11, November 2025.
Human endogenous retroviruses (HERVs), remnants of ancient retroviral integrations into the human genome, are modulated by viral infections, genetic inheritance, and triggers including environmental factors, epigenetic dysregulation, oncogene activation, and aging.
Can Chen, Yanru Cui, Shixiang Wang, Yuze Yang, Zunpeng Liu, Suhan Jin, Fangqian Shen, Udo Gaipl, Hu Ma, Jian‐Guo Zhou   +9 more
wiley   +1 more source

The Multiple-Locus Variable Number Tandem Repeat Analysis (MLVA) of Staphylococuss aureus clinical isolates recovered from the Provincial Specialist Hospital in Lublin, Poland

Current Issues in Pharmacy and Medical Sciences
Understanding the epidemiology and evolution of Staphylococcus aureus (SA) is crucial for implementing effective infection prevention and control measures.
Bogut Agnieszka, Grzegorczyk Agnieszka, Kuszneruk Dominik   +2 more
doaj   +1 more source

Genetic Basis of the Negative Response to the Use of Triptans for the Treatment of Migraine—A Systematic Review and Meta‐Analysis

Brain and Behavior, Volume 15, Issue 10, October 2025.
To systematize the genetic basis correctly associated with nonresponse to triptan, we revised etiological studies on Web of Science, Embase, and PubMed until 2023. We found that only polymorphisms in the SLC6A4, 5‐HT1B, and COMT genes have a stronger association with this condition. More robust studies are needed to increase this certainty.
Victoria Gomes Andreata, Ruan Pablo Duarte Freitas, Jéssica da Silva Nascimento, Patrícia Sodré Araújo, Felipe Eustáquio dos Santos Guedes, João Vítor Benjamim Pires, Narel Moita Carneiro Nogueira Falcão, Natasha da Silva Leitão, Alcylene Carla de Jesus dos Santos, Ana Patrícia Pascoal Queiroz, Astria Ferrão Dias Gonzales, Maica Matos Leão, Emília Katiane Embiruçu de Araújo Leão, Juliana Côrtes Freitas, Acássia Benjamim Leal Pires   +14 more
wiley   +1 more source

Humanized Mouse Models for Type 1 Diabetes

Current Protocols, Volume 5, Issue 10, October 2025.
Abstract T cell–mediated autoimmune type 1 diabetes (T1D) is under complex polygenic control in both humans and the NOD mouse model. However, in both species, particular major histocompatibility complex (MHC; designated HLA in humans) haplotypes provide the primary T1D risk factor. Both MHC/HLA class I and II variants interactively contribute to T1D by
David V. Serreze, Marissa Tousey‐Pfarrer, Jeremy J. Racine   +2 more
wiley   +1 more source

Evaluation of the genetic profiles of Brucella with different biotypes using MLVA and MLST techniques

Animal Diseases
Brucella, the causative agent of brucellosis, is a globally significant zoonotic pathogen with serious public health implications. Understanding the molecular and genetic characteristics of Brucella species is crucial for the precise prevention, control,
Chaoyue Guo, Xiaojie Zhu, Yaqin Zhang, Xiaowei Peng, Weifeng Sun, Kaixuan Guo, JIandong Zhang, Xiaoqian Zhang, Junping Li, Zhengfei Liu   +9 more
doaj   +1 more source

A multi locus variable number of tandem repeat analysis (MLVA) scheme for Streptococcus agalactiae genotyping

BMC Microbiology, 2011
Background Multilocus sequence typing (MLST) is currently the reference method for genotyping Streptococcus agalactiae strains, the leading cause of infectious disease in newborns and a major cause of disease in immunocompromised children and adults.
Mereghetti Laurent, Quentin Roland, Rosenau Agnès, Domelier Anne-Sophie, Lartigue Marie-Frédérique, Baty Gaelle, Pourcel Christine, Haguenoer Eve, Lanotte Philippe   +8 more
doaj   +1 more source