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Multiple Myeloma, Version 3.2021, NCCN Clinical Practice Guidelines in Oncology.

The Journal of the National Comprehensive Cancer Network, 2020
Multiple myeloma is a malignant neoplasm of plasma cells that accumulate in bone marrow, leading to bone destruction and marrow failure. This manuscript discusses the management of patients with solitary plasmacytoma, smoldering multiple myeloma, and ...
Shaji K. Kumar   +28 more
semanticscholar   +1 more source

History of Multiple Myeloma

2004
Multiple Myeloma has been recognized since Ancient Times. The first well-documented case was reported in 1844 by Samuel Solly. The most commonly recognized case is that of Thomas Alexander McBean, a highly respectable tradesman from London in 1850. Mr.
Robert A. Kyle, David P. Steensma
openaire   +3 more sources

Multiple myeloma

Nature Reviews Disease Primers
Multiple myeloma (MM) is a haematological lymphoid malignancy involving tumoural plasma cells and is usually characterized by the presence of a monoclonal immunoglobulin protein. MM is the second most common haematological malignancy, with an increasing global incidence.
Florent Malard   +7 more
openaire   +2 more sources

Multiple myeloma

Seminars in Oncology Nursing, 1996
To review the epidemiology, pathogenesis, clinical features, diagnosis, treatment, and nursing management of multiple myeloma.Review articles, research studies, and book chapters related to multiple myeloma.Despite insights into the immunobiology of multiple myeloma and the advances in intensive therapy and supportive care, multiple myeloma remains an ...
openaire   +2 more sources

Bisphosphonates in multiple myeloma

2002
Multiple myeloma is a disease characterized by the neoplastic proliferation of a clone of plasma cells that can lead to bone destruction. Bisphosphonates are specific inhibitors of osteoclastic activity. Therefore, there is a pharmacological basis for their use in multiple myeloma. However, the exact clinical role of bisphosphonates in multiple myeloma
B, Djulbegovic   +8 more
openaire   +5 more sources

Multiple myeloma

Current Opinion in Oncology, 1994
The mortality associated with multiple myeloma is due to the progressive accumulation of a clonal population of plasma cells in the bone marrow. Tumor cells may also be found in the blood and other extramedullary sites, especially in the terminal stages of the disease.
M V, Seiden, K C, Anderson
openaire   +2 more sources

Multiple Myeloma

Medical Clinics of North America, 1984
Multiple myeloma is a malignant neoplasm of plasma cells involving bone and bone marrow, frequently leading to extensive skeletal destruction, bone marrow failure, renal dysfunction, and problems related to the monoclonal myeloma proteins. Vigilant supportive care and effective chemotherapy can prolong survival and improve the quality of life in most ...
openaire   +2 more sources

Homozygous BCMA gene deletion in response to anti-BCMA CAR T cells in a patient with multiple myeloma

Nature Network Boston, 2021
Matteo Da Via   +26 more
semanticscholar   +1 more source

The multiple myeloma microenvironment is defined by an inflammatory stromal cell landscape

Nature Immunology, 2021
M. D. de Jong   +15 more
semanticscholar   +1 more source

MULTIPLE MYELOMA

AJN, American Journal of Nursing, 1975
D, Schumann, P, Patterson
openaire   +3 more sources

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