Results 71 to 80 of about 773,408 (302)
Multi-marker approach using procalcitonin, presepsin, galectin-3, and soluble suppression of tumorigenicity 2 for the prediction of mortality in sepsis [PDF]
, 2017 Background: Biomarker could be objective and reliable tools to predict mortality in sepsis. We explored the prognostic utilities of emerging biomarkers in septic patients and questioned whether adding biomarkers to the clinical variables would improve ...
Hanah Kim +5 more
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
A case of gas gangrene with fatal outcome (gas gangrene: A case report) [PDF]
Serbian Journal of Anesthesia and Intensive TherapyIntroduction: The clinical course of gas gangrene is often rapidly progressive, with a fatal outcome in up to 80% of treated cases. The disease is most commonly a consequence of trauma or surgical interventions.
Pavić Slađana +3 more
doaj +1 more source
Two cases of acute renal failure associated with non-typhoid Salmonella infection [PDF]
, 1988 Two cases of acute renal failure associated with non-typhoid Salmonella infection are reported. Case 1: A 49-year-old man was admitted with the complaint of severe watery diarrhea and oliguria. Stool culture revealed Salmonella typhimurium.
河田, 幸道 +5 more
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Successful Treatment of Multiple Organ Failure After Wasp Stings in an Elderly Patient
International Journal of Gerontology, 2012 Although all kinds of complication have been reported after wasp stings, multiple organ failure following wasp attacks is very rare. In the past, the mortality of patients with multiple organ failure treated by conventional therapy after wasp stings was ...
Wang Han-Min +6 more
doaj +1 more source
Luka Tusuk Tembus Hati dan Pankreas Berakibat Dic yang Mematikan (sebuah Laporan Kasus) [PDF]
, 2013 Most cases of forensic clinic that was treated in hospital just use medical records to be poured into the visum et repertum clinic. Rarely asked to do an autopsy.
Ika Pristianti, RAY. Kusparwati +2 more
core
Present and future pharmacotherapeutic agents in heart failure: an evolving paradigm [PDF]
, 2016 Many conditions culminate in heart failure (HF), a multi-organ systemic syndrome with an intrinsically poor prognosis. Pharmacotherapeutic agents that correct neurohormonal dysregulation and haemodynamic instability have occupied the forefront of ...
Abozguia +119 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Modern principles of treatment of the serious multisystem injuries
Бюллетень сибирской медицины, 2009 The analytical survey is concerned with the organizational aspects of the integrated study and thorough investigation of the problem of treatment of serious mechanical injuries.
A. V. Shteinle
doaj +1 more source