Results 81 to 90 of about 11,046,276 (309)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Kinesiotherapeutic Possibilities and Molecular Parameters in Multiple Sclerosis

open access: yesSclerosis
Multiple sclerosis (MS) is a chronic and incurable neurological disease of the central nervous system. Three main forms of the disease have been distinguished: relapsing–remitting form (RRMS), secondary progressive form (SPMS), and primary progressive ...
Katarzyna Wiszniewska   +6 more
doaj   +1 more source

Multiple Parameters Estimation of BOC Signal in Multipath Environment

open access: yesMATEC Web of Conferences, 2018
For the multiple parameters estimation of BOC signal at the low SNR and multipath environment, the method which applies the characteristics of cyclic spectrum is developed. Firstly, the cyclic spectrum function of multipath BOC signal is derived.
Wang Yang, Zhou Yang
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Estimating the parameters of multiple chirp signals

open access: yesJournal of Multivariate Analysis, 2015
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ananya Lahiri, Debasis Kundu, Amit Mitra
openaire   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

The study of intelligence wireless sensor array to monitor parameter of air

open access: yesTongxin xuebao, 2008
A multiple target air parameters monitoring scheme with the help of the wireless intelligence sensor network which is built up with multiple sensors was proposed.The design of the wireless intelligence array sensor was considered,the method to configure ...
ZHONG Yuan-chang1   +3 more
doaj   +2 more sources

A comparative analysis of groundwater quality in a suburban area of Bangladesh

open access: yesScientific Reports
The necessity to explore groundwater for agricultural and domestic purposes has grown in importance because of overexploitation, depletion, and growing contamination of surface water supplies. This study investigates the relationships between groundwater
Dinobandhu Biswas   +6 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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