Results 61 to 70 of about 11,046,276 (309)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Protein evolution depends on multiple distinct population size parameters
BMC Evolutionary Biology, 2018 That population size affects the fate of new mutations arising in genomes, modulating both how frequently they arise and how efficiently natural selection is able to filter them, is well established.
Alexander Platt +2 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
ESTIMATION OF SIGNAL PARAMETERS FOR MULTIPLE TARGET LOCALIZATION [PDF]
ICTACT Journal on Communication Technology, 2014 Target detection and localization is an active research area due to its importance in a wide range of application such as biomedical and military applications.
X. Susan Christina +2 more
doaj
Beyond Genetics—Stratified and Personalised Medicines Using Multiple Parameters
Pharmaceuticals, 2010 Prescribers have been practicing stratified medicine for many years. Patient characteristics, usually non-genetic, including age, comorbidities and concomitant medications are taken into account when deciding which drug to prescribe.
Richard Peck, Patrick Smith
doaj +1 more source
ROOT LOCI WITH MULTIPLE GAIN PARAMETERS
IFAC Proceedings Volumes, 1983 Abstract The multivariable root-locus concept is generalised by allowing for independently variable gain parameters in different feedback paths. This leads to the consideration of a family of root-loci, each corresponding to a ray in the gain space.
P.A. Cook, C.S. Hall
openaire +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Medical Remote Monitoring of Multiple Physiological Parameters Based on Wireless Embedded Internet
IEEE Access, 2020 In view of the current situation, that physiological parameter monitoring systems can only achieve local monitoring, and the multi-physiological parameter monitors are large, expensive, and disadvantageous to remote monitoring.
Sheng Ding, Xiaoyan Wang
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Differences in multiple immune parameters between Indian and U.S. infants. [PDF]
PLoS ONE, 2018 To compare immune phenotypes across two geographic and ethnic communities, we examined umbilical cord blood by flow cytometry and Luminex in parallel cohorts of 53 newborns from New Delhi, India, and 46 newborns from Stanford, California.
Deepak K Rathore +17 more
doaj +1 more source