Results 91 to 100 of about 944,161 (303)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Equivariant Variance Estimation for Multiple Change-point Model

, 2023
The variance of noise plays an important role in many change-point detection procedures and the associated inferences. Most commonly used variance estimators require strong assumptions on the true mean structure or normality of the error distribution ...
Xiao, Han, Niu, Y.S., Xiao, H., Niu, Yue Selena, Hao, Ning, Hao, N.   +5 more
core   +1 more source

Using multiple-point geostatistics for geomodeling of a vein-type gold deposit

Applied Computing and Geosciences
Geostatistical cascade modeling of Mineral Resources is challenging in vein-type gold deposits. The narrow shape and long-range features of these auriferous veins, coupled with the paucity of drill-hole data, can complicate the modeling process and make ...
Aida Zhexenbayeva, Nasser Madani, Philippe Renard, Julien Straubhaar   +3 more
doaj   +1 more source

Implications of heterogeneity on transport simulations at large scale: the Morroa aquifer case

Revista Facultad de Ingeniería Universidad de Antioquia, 2014
The Morroa aquifer located in Sucre state (northern Colombia) represents the exclusive source of water supply for nearly 500.000 people, including the capital of the state Sincelejo.
Anibal Jose Pérez-García, Oscar García-Cabrejo, Nelson Obregón-Neira   +2 more
doaj   +1 more source

Conditioning of multiple-point statistics simulations to indirect geophysical data

Computers & Geosciences
Multiple-point statistical (MPS) simulation methods have gained widespread adoption across various Earth science disciplines. They offer a versatile framework for simulating intricate spatial patterns and heterogeneity in both surface and subsurface structures.
Shiran Levy, Lea Friedli, Grégoire Mariéthoz, Niklas Linde   +3 more
openaire   +2 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Semi-parametric dynamic time series modelling with applications to detecting neural dynamics [PDF]

, 2007
This paper illustrates the theory and applications of a methodology for non-stationary time series modeling which combines sequential parametric Bayesian estimation with non-parametric change-point testing.
Smith, J. Q., Rigat, Fabio
core  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Nonparametric maximum likelihood approach to multiple change-point problems [PDF]

, 2014
In multiple change-point problems, different data segments often follow different distributions, for which the changes may occur in the mean, scale or the entire distribution from one segment to another.
Wang, Z, Zou, C, Feng, L, Yin, G
core   +1 more source

Network Models to Organize a Dispersed Literature: The Case of Misunderstanding Analysis of Covariance

Journal of European Psychology Students, 2018
We outline a network method to synthesize a literature overview from search results obtained by multiple team members. Several network statistics are used to create a single representativeness ranking.
Koen Derks, Julian Burger, Johnny van Doorn, Jolanda J. Kossakowski, Dora Matzke, Ludovica Atticciati, Julia Beitner, Viket Benzesin, Anne L. de Bruijn, Tara R. H. Cohen, Elisa P. A. Cordesius, Marit van Dekken, Nora Delvendahl, Simone Dobbelaar, Eva R. Groenendijk, Merel E. Hermans, Anu P. Hiekkaranta, Ria H. A. Hoekstra, Agnes M. Hoffmann, Sally A. M. Hogenboom, Sercan Kahveci, Irina J. Karaban, Sofieke Kevenaar, Jurriaan L. te Koppele, Anne-wil Kramer, Emese Kroon, Šimon Kucharský, Ricardo Lieuw-On, Gaby Lunansky, Timo P. Matzen, Annemarie Meijer, Annika Nieper, Laura de Nooij, Leonie Poelstra, Wikke J. van der Putten, Alexandra Sarafoglou, Jessica V. Schaaf, Sara A. J. van de Schraaf, Steven van Schuppen, Manon H. M. Schutte, Mitja Seibold, Scarlett K. Slagter, Aishah C. Snoek, Selina Stracke, Zenab Tamimy, Bram Timmers, Han Tran, Elizabeth S. Uduwa-Vidanalage, Laura Vergeer, Linos Vossoughi, Dilan E. Yücel, Eric-Jan Wagenmakers   +51 more
doaj   +1 more source