Results 61 to 70 of about 951,521 (353)

The long-term impact of folic acid in pregnancy on offspring DNA methylation : follow-up of the Aberdeen folic acid supplementation trial (AFAST) [PDF]

, 2018
Funding This work was supported by the NIHR Bristol Biomedical Research Centre at the University Hospitals Bristol NHS Foundation Trust and the University of Bristol.
Atkinson, Charlotte, Bhattacharya, Sohinee, Campbell, Doris, Gaunt, Tom, Hall, Marion, Herbert, Georgia, Kazmi, Nabila, McArdle, Wendy, Ness, Andy, Relton, Caroline L., Richmond, Rebecca C., Ring, Susan, Sharp, Gemma C., Smith, George Davey, Taylor, Caroline   +14 more
core   +3 more sources

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

INTRAUTERINE INSEMINATION (IUI) AND MULTIPLE PREGNANCY

Zdravniški Vestnik, 2003
Background. Multiple pregnancies are relatively common complication of IUI following ovarian stimulation due to increased number of the preovulatory follicles in the procedure.
Sašo Drobnič
doaj  

Comparative assessment of changes ADAMTS-13/von Willebrand factor axis in singleton and bichorial biamniotic pregnancy

Акушерство, гинекология и репродукция
Aim: to compare changes in the ADAMTS-13 metalloproteinase/von Willebrand factor (vWF) axis in pregnant women with spontaneous or following in vitro fertilization (IVF) singleton and bichorial biamniotic pregnancies.Materials and Methods.
F. Е. Yagubova, V. O. Bitsadze, N. V. Samburova, J. Kh. Khizroeva, A. D. Makatsariya   +4 more
doaj   +1 more source

Preliminary Study of Iron Concentration in the Human Placenta in Twin Pregnancies

Biomolecules, 2023
Background: Pregnancy significantly increases the demand for iron (Fe) in the female body to facilitate maternal blood volume expansion, placental development, and fetal growth. As Fe flux in pregnancy is significantly influenced by the placenta, the aim
Konrad Grzeszczak, Patrycja Kapczuk, Patrycja Kupnicka, Maciej Mularczyk, Sebastian Kwiatkowski, Dariusz Chlubek, Danuta Kosik-Bogacka   +6 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

QUALITY OF BLASTOCYST IN VITRO AND MULTIPLE PREGNANCIES

Zdravniški Vestnik, 2003
Background. The blastocysts, obtained from in vitro fertilization, have different morphologic characteristics. The aim of the study is to investigate the effect of morphology of transferred blastocysts on pregnancy and multiple pregnancy rate.Methods ...
Borut Kovačič, Mojca Čižek Sajko, Veljko Vlaisavljević   +2 more
doaj  

Heterotopic Pregnancy, It is Such a Rare Finding? [PDF]

, 2016
Heterotopic pregnancy is a multiple pregnancy with simultaneous implantation of the embryos at two or more distinct locations. Risk factors, epidemiology, signs, symptoms, sonographic findings and management options are reviewed.
Giacomello, F, Larciprete, G, Valenzise, H   +2 more
core  

Miscarriage, stillbirth and congenital malformation in the offspring of UK veterans of the first Gulf war.

, 2004
OBJECTIVES: To assess whether the offspring of UK veterans of the first Gulf war are at increased risk of fetal death or congenital malformation. METHOD: This was a retrospective reproductive cohort study of UK Gulf war veterans and a demographically ...
Davies, Graham, Doyle, Pat, Lewis, Samantha, Maconochie, Ian, Maconochie, Noreen, Pelerin, Margo, Prior, Susan   +6 more
core   +1 more source