Results 211 to 220 of about 9,631,377 (247)

A pancancer analysis of the clinical and genomic characteristics of multiple primary cancers. [PDF]

Sci Rep
Zhang B, He L, Zhou C, Cheng X, Li Q, Tang Y, Li F, Huang T, Tu S.   +8 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Synchronous multiple primary cancers of the gastric antrum and transverse colon with advanced polycystic liver and kidney disease: Case report

Asian Journal of Surgery
Fan Zhang, Leping Peng, Fang Ma, Lili Wang   +3 more
doaj   +1 more source

Risk of multiple primary cancers in patients with atypical fibroxanthoma/pleomorphic dermal sarcoma: A SEER analysis. [PDF]

JAAD Int
Shah VK, Nijhawan RI.
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Multiple Primary Cancers With Hematologic Malignancies and Germline Predisposition: A Case Series. [PDF]

Ann Lab Med
Yun J, Lee DS, Lee S, Yun H.
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Case report of multiple primary cancers and results of genetic testing to preliminarily explore their pathogenesis. [PDF]

SAGE Open Med Case Rep
Hong Z, Tongsong Z, Cunhai C, Xiao L, Haiping S.   +4 more
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Incidence and Characteristics of Multiple Primary Cancers: A 20-Year Retrospective Study of a Single Cancer Center in Korea. [PDF]

Cancers (Basel)
Kwon JH, Kim H, Lee JK, Hong YJ, Kang HJ, Jang YJ.   +5 more
europepmc   +1 more source