Results 101 to 110 of about 28,675 (247)

Frailty and Fitness in Older Adults With Acute Myeloid Leukemia: From Chronological Age to Multiparametric Assessment

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Acute Myeloid Leukemia predominantly affects older adults, who often present with comorbidities, functional impairment, and frailty, limiting eligibility for intensive chemotherapy or allogeneic transplantation. Historically, treatment options were restricted to hypomethylating agents, low‐dose cytarabine, hydroxyurea, or supportive care, with
Antonella Bruzzese   +11 more
wiley   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra   +5 more
wiley   +1 more source

Male genital lichen sclerosus

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Male genital lichen sclerosus is driven by chronic, occluded exposure of susceptible genital epithelium to urine, rather than infection or autoimmunity. This review synthesizes clinical, anatomical and molecular evidence showing how microincontinence and occlusion initiate inflammation, fibrosis and carcinogenesis, and explains the curative effect of ...
Georgios Kravvas   +3 more
wiley   +1 more source

Neural correlates of pure apathy in multiple sclerosis: An exploratory neuroimaging study

open access: yesJournal of Neuropsychology, EarlyView.
Abstract Pure apathy is relatively common in people with Multiple Sclerosis (PwMS), but its neural mechanisms remain unexplored. Therefore, we investigated the neural correlates of pure apathy in PwMS, differentiating it from depression. Sixty‐two PwMS underwent neuropsychological assessments and Magnetic Resonance Imaging scans.
Valentina Torchia   +7 more
wiley   +1 more source

Preservation of positive emotion recognition in patients with multiple sclerosis: Artefact related to methodological issues or real feature of the disorder?

open access: yesJournal of Neuropsychology, EarlyView.
Abstract Prior studies in multiple sclerosis (MS) suggest preserved recognition of positive emotions despite deficits for negative ones, but this dissociation may reflect methodological limitations (valence‐asymmetry: positive‐valence being limited to happiness/joy in basic‐emotion sets). This study tested whether emotion–recognition deficits in MS are
Laurent Zikos   +6 more
wiley   +1 more source

Comparison of efficacy and safety of oral agents for the treatment of relapsing–remitting multiple sclerosis

open access: yesDrug Design, Development and Therapy, 2017
Cristina Guarnera, Placido Bramanti, Emanuela Mazzon IRCCS Centro Neurolesi “Bonino-Pulejo”, Messina, Italy Abstract: In the therapeutic scenario of disease-modifying therapies for relapsing–remitting multiple sclerosis, the ...
Guarnera C, Bramanti P, Mazzon E
doaj  

Health Literacy and Unmet Needs in Patients With Multiple Sclerosis: A Cross‐Sectional Study

open access: yesJournal of Clinical Nursing, EarlyView.
ABSTRACT Aims To identify a correlation between unmet needs and HL levels in people with Multiple Sclerosis (pwMS) and to evaluate how sociodemographic characteristics influence HL levels and unmet needs. Design A cross‐sectional study. Methods The study was conducted using a questionnaire including the HLS19‐Q12 to assess HL and the Long‐term Unmet ...
Francesco Pastore   +6 more
wiley   +1 more source

Advances in the treatment of systemic lupus erythematosus: Biologicals, small‐molecular agents, and cell‐depleting therapies coming to the clinic

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Systemic lupus erythematosus (SLE; lupus) remains a particular challenge for the practicing clinician on account of its chronic undulating and unpredictable course, its diverse manifestations, and—until recently—limited treatment options all associated with considerable downsides.
Ronald van Vollenhoven
wiley   +1 more source

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