Results 111 to 120 of about 28,675 (247)

CD4+ T Cells Predict Relapse in Pemphigus Vulgaris Treated With Rituximab: A Retrospective Study

Oral Diseases, EarlyView.
ABSTRACT Objective This study evaluated the CD4+ T‐cell role in mediating post‐Rituximab Pemphigus vulgaris (PV) relapse, comparing CD4+ count and CD4+/CD20+ ratio between patients who achieved remission and those who relapsed. Methods The clinical course of 27 PV patients treated with Rituximab was evaluated after a 32‐month median follow‐up. CD4+ and
Simone Liguori, Noemi Coppola, Elvira Ruoppo, Federica Canfora, Gabriele Mignogna, Ilaria Mormile, Antonia Fiore, Giuseppe Castaldo, Michele Davide Mignogna, Stefania Leuci   +9 more
wiley   +1 more source

Understanding the Reproductive Life Planning Experiences of People With Disabilities in Ontario, Canada: A Qualitative Exploration

Perspectives on Sexual and Reproductive Health, EarlyView.
ABSTRACT Introduction Reproductive life planning can be a valuable component of reproductive health promotion. However, little is known about attitudes, desires, and intentions regarding pregnancy among people with disabilities. This exploratory qualitative study aimed to understand the reproductive life planning experiences of women and gender‐diverse
Momina Khan, Hilary K. Brown, Yona Lunsky, Lesley A. Tarasoff   +3 more
wiley   +1 more source

Clinical Predictors of Response in Chronic Graft‐Versus‐Host Disease: Results From the “Predicting the Quality of Response to Specific Treatments (PQRST)” Trial

American Journal of Hematology, Volume 101, Issue 9, Page 2280-2287, September 2026.
ABSTRACT Despite significant progress in chronic GVHD therapies, challenges remain in understanding pleomorphic phenotypes and varying responses to treatment. The aim of this study was to identify predictors of treatment response. We conducted a prospective, observational cohort study of patients beginning first‐, second‐, or third‐line systemic ...
Betty K. Hamilton, Lynn Onstad, Paul A. Carpenter, Joseph Pidala, George Chen, Corey Cutler, Najla El Jurdi, Nosha Farhadfar, Mark Juckett, Carrie L. Kitko, Catherine J. Lee, Stephanie J. Lee   +11 more
wiley   +1 more source

Examination of High-Level Language Skills in 2 Phases of Multiple Sclerosis (Relapsing-Remitting & Secondary Progressive) in Comparison With Healthy Counterparts. [PDF]

Med J Islam Repub Iran
Rahimifar P, Isazadeh R, Soltani M, Ghobadi R, Boazar A, Abaeian G, Aliabdi L, Majdinasab N, Amini P.   +8 more
europepmc   +1 more source

Proinflammatory Epstein–Barr Virus Antibody Functions Track with Disease Activity in Multiple Sclerosis

Annals of Neurology, Volume 100, Issue 3, Page 547-558, September 2026.
Objective Epstein–Barr virus (EBV) has been implicated in the pathogenesis of multiple sclerosis (MS). Elevated immunoglobulin G (IgG) titers against EBV nuclear antigen 1 (EBNA1) represent the most consistent serological marker of MS risk, with levels remaining persistently elevated following disease onset.
Malina Behrens, Paula Terroba‐Navajas, Eline A.J. Willemse, Sabine Schädelin, Manuel Comabella, Christian Münz, Gordan Lauc, Yannic Bartsch, Jens Kuhle, Jan D. Lünemann   +9 more
wiley   +1 more source

Ferroptosis: Newly Emerged Regulator for Human Disease

MedComm, Volume 7, Issue 9, September 2026.
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao, Lin Ye, Tianqi Jiang, Mengyuan Liu, Yuxia Zhou   +4 more
wiley   +1 more source

Possible Contribution of Multiple Sclerosis Pathology to Treatment‐Resistant Schizophrenia: A Case Study

Neuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
A case of multiple sclerosis detected by brain MRI during evaluation for modified electroconvulsive therapy in the long‐term course of schizophrenia. This case discusses the clinical overlap between multiple sclerosis pathology and treatment‐resistant schizophrenia. ABSTRACT Multiple sclerosis (MS) can present with neurological and psychiatric symptoms
Sho Miura, Atsuko Nagaoka, Mizuki Hino, Risa Shishido, Masataka Hatano, Yuto Hosogai, Kazusa Miyahara, Yuta Oba, Kimihiko Kaneko, Yasuto Kunii, Hiroaki Tomita   +10 more
wiley   +1 more source

A Fast, Flexible Simulation Framework for Bayesian Adaptive Designs—The R Package BATSS

Pharmaceutical Statistics, Volume 25, Issue 5, September/October 2026.
ABSTRACT The use of Bayesian adaptive designs for randomised controlled trials has been hindered by the lack of software readily available to statisticians. We have developed a new software package (Bayesian Adaptive Trials Simulator Software—BATSS) for the statistical software R, which provides a flexible structure for the fast simulation of Bayesian ...
Dominique‐Laurent Couturier, Rainer Puhr, Stephane Heritier, Thomas Jaki, Elizabeth G. Ryan   +4 more
wiley   +1 more source

Correlation Is Not Prediction: Reassessing Predictive MRI Evidence in Guidelines for Persons With Relapsing-Remitting Multiple Sclerosis. [PDF]

J Cent Nerv Syst Dis
Minas D, Buchka S, Havla J, Mansmann U.
europepmc   +1 more source

The Neurovascular Niche: A Gathering Venue for Neuroinflammation and Remyelination in Multiple Sclerosis

Acta Physiologica, Volume 242, Issue 9, September 2026.
ABSTRACT In the central nervous system (CNS), the tissue microenvironment is continuously monitored and regulated to secure the unobstructed function of neurons and of their networks. This is a key function of the neurovascular niche (NVN), which is the interface between the cells of the nervous tissue and the cells and the content of blood vessels. It
Ilias Kazanis, Maria Elena Silva, Alerie G. de la Fuente, Fernando de Castro, Francisco J. Rivera   +4 more
wiley   +1 more source