Results 141 to 150 of about 28,675 (247)

Vitamin D Supplementation and its Effect on Relapse Frequency and MRI Activity in Adults With Multiple Sclerosis: A Systematic Review

Brain and Behavior, Volume 16, Issue 8, August 2026.
This systematic review examined whether vitamin D supplementation reduces disease activity in adults with multiple sclerosis. Across 11 primary studies, vitamin D was not consistently associated with reduced relapse frequency, though MRI‐based measures showed a modest and inconsistent signal, leaving its clinical benefit uncertain.
Kamren Hall, Jessica Renteria, Elizabeth Fernandez, Janique Abrahams, Saajan Bhakta   +4 more
wiley   +1 more source

Cost-Effectiveness of Dimethyl Fumarate Versus Teriflunomide in Patients With Relapsing-Remitting Multiple Sclerosis (RRMS) in Iran. [PDF]

Health Sci Rep
Poursadeghfard M, Farjah Y, Rezaee M, Momtahan N, Morowvat MH, Gholami A, Keshavarz K.   +6 more
europepmc   +1 more source

H Syndrome Associated With Pure Red Cell Aplasia, Rosai–Dorfman Disease, and Sensorineural Hearing Loss: Phenotypic Variability in Three Children With the Same SLC29A3 Mutation

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT H syndrome is a rare autosomal recessive disorder caused by mutations in the SLC29A3 gene. We report three pediatric patients with a homozygous c.1309G>A (p.Gly437Arg) mutation presenting with distinct phenotypic variations. These cases expand the clinical spectrum and emphasize the importance of early genetic diagnosis and family counseling.
Mohammad Najajrah, Hadeel I. Bouzia, Nermin K. Darawi, Fatima S. Hajjaj, Nour H. Moosa, Noor M. Awad   +5 more
wiley   +1 more source

Investigating Depression and MRI Associations in Middle Eastern Relapsing-Remitting Multiple Sclerosis. [PDF]

J Biomed Phys Eng
Pishdad P, Zeinali-Rafsanjani B, Poursadeghfard M, Kalaee M, Ostovarfar J, Salehi A.   +5 more
europepmc   +1 more source

Chronic Recurrent Multifocal Osteomyelitis in a Pediatric Patient: An Uncommon Case With Diagnostic Challenge

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Chronic Recurrent Multifocal Osteomyelitis (CRMO) is a rare autoinflammatory bone disorder that primarily affects children and adolescents. It is characterized by recurrent episodes of bone pain with sterile inflammatory lesions, often resembling infection or malignancy.
Dosti Regmi, Madhur Bhattarai, Sujata Bhandari, Saurav Jha, Akriti Baral   +4 more
wiley   +1 more source

The cGAS–STING Pathway Drives Astrocyte‐Mediated Demyelination in Multiple Sclerosis Through Clusterin Secretion

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
In multiple sclerosis, astrocytes detect extracellular DNA via the cGAS–STING pathway, triggering Clusterin secretion that induces oligodendrocyte apoptosis and demyelination. Pharmacological STING inhibition with H‐151 suppresses this neurotoxic cascade, preserves myelin integrity, and ameliorates clinical disability in experimental autoimmune ...
Shengfei Hu, Xia Xiao, Xi Cheng, Yiying Huang, Tingting Cui, Shishi Shen, Chunping Cui, Li Xiao, Hanzhang Tan, Wei Qiu, Yipeng Zhao, Rui Li   +11 more
wiley   +1 more source

Functional Connectivity Alterations of the Central Autonomic Network in Multiple Sclerosis: Links to Fatigue and Aerobic Training Effects. [PDF]

Neurol Neuroimmunol Neuroinflamm
Guido G, Valsasina P, Morozumi T, Preziosa P, Romanò F, Rocca MA, Filippi M.   +6 more
europepmc   +1 more source

Ofatumumab Treatment for Refractory Generalized Myasthenia Gravis Post‐Lung Adenocarcinoma Resection: A Case Report and Mechanistic Insight

Immunity, Inflammation and Disease, Volume 14, Issue 8, August 2026.
ABSTRACT Background Myasthenia gravis (MG), an autoimmune neuromuscular disorder, may rarely coexist with malignancies such as lung cancer. Case Presentation This case report presents the first documented use of ofatumumab, a fully human anti‐CD20 monoclonal antibody, in a 75‐year‐old female with acetylcholine receptor (AChR)‐antibody‐positive ...
Xia Long, Yanwen Xu, Juan Xiong, Wenfeng Peng, Jinhua Qiu, Yanxia Zhou   +5 more
wiley   +1 more source

Defining Activity-Based Subgroups in Multiple Sclerosis: A Review and Framework Proposal. [PDF]

Eur J Neurol
Lopez Manzano C, Rice CM, Tallantyre E, Cooper C, Cooper C, Wang H, Tomlinson E, Sadek A, Rao-Middleton A, Thom H, Whiting P.   +10 more
europepmc   +1 more source

Resolution of Paraneoplastic Cutaneous Angioendotheliomatosis After CAR T‐Cell Therapy in TP53‐Deleted CLL: A Case Report

eJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Cutaneous manifestations of chronic lymphocytic leukemia (CLL) are heterogeneous and may result from leukemic infiltration, secondary malignancies, infectious complications, or reactive inflammatory processes. Reactive angioendotheliomatosis (RAE) is a rare vascular proliferation that has only infrequently been reported in association with ...
Feras Alfraih, Mostafa F. Mohammed Saleh, David Li, Razan Mohty, Mohamed Kharfan‐Dabaja   +4 more
wiley   +1 more source