Results 91 to 100 of about 458,215 (302)

Insights for Healthcare Providers on Shared Decision-Making in Multiple Sclerosis: A Narrative Review

Neurology and Therapy
Shared decision-making (SDM) between the patient and their healthcare provider (HCP) in developing treatment plans is increasingly recognized as central to improving treatment adherence and, ultimately, patient outcomes.
Sharon Stoll, Kathleen Costello, Scott D. Newsome, Hollie Schmidt, Amy B. Sullivan, Barry Hendin   +5 more
doaj   +1 more source

Concurrent TNFRSF1A R92Q and pyrin E230K mutations in a child with multiple sclerosis [PDF]

, 2010
We report a 16-year-old female patient with a severe course of multiple sclerosis and concomitant symptoms suggestive of a hereditary autoinflammatory disease.
K Huss, R Hohlfeld, Kümpfel, T., T Kümpfel, Heinen, F., Mueller-Felber, W., A Blaschek, Blaschek, A., Huss, K., Hohlfeld, R., F Heinen, Blaschek, Astrid, Lohse, P., Borggraefe, I., P Lohse, W Mueller-Felber, I Borggraefe   +16 more
core   +1 more source

Assessment of Multiple Aspects of Upper Extremity Function Independent From Ambulation in Patients With Multiple Sclerosis

, 2023
BACKGROUND Upper extremity function (UEF) is often compromised in multiple sclerosis (MS), although its importance is regularly underrecognized relative to ambulation.
Uitdehaag, Bernard M J, Dorn, Jonas, D'Souza, Marcus, Marcus D’Souza, Ludwig Kappos, Kamm, Christian P, Jonas Dorn, Bernard M.J. Uitdehaag, Dahlke, Frank, Kappos, Ludwig, Saskia Steinheimer, Diederich, Manuela, Jessica, Burggraaff, Christian P. Kamm, Frank Dahlke, Walsh, Lorcan, Steinheimer, Saskia, van Munster, Caspar E P, Burggraaff Jessica, Lorcan Walsh, Caspar E.P. van Munster, Manuela Diederich   +21 more
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Lifetime exposure to smoking and substance abuse may be associated with late-onset multiple sclerosis: a population-based case-control study

BMC Neurology
Background Late-onset multiple sclerosis (LOMS), defined as the development of MS after the age of 50, has shown a substantial surge in incidence rates and is associated with more rapid progression of disability.
Naghmeh Abbasi Kasbi, Sajjad Ghane Ezabadi, Kosar Kohandel, Faezeh Khodaie, Amir Hossein Sahraian, Sahar Nikkhah Bahrami, Mahsa Mohammadi, Amir Almasi-Hashiani, Sharareh Eskandarieh, Mohammad Ali Sahraian   +9 more
doaj   +1 more source

D-KEFS ST Failure Identifies Multiple Sclerosis Patients With Worse Objective and Self-Perceived Physical and Cognitive Disability

Frontiers in Psychology, 2019
Background and Objectives: The Brief Repeatable Battery of Neuropsychological Test (BRB-NT) does not explore the executive functions. We combined BRB-NT and Delis-Kaplan Executive Function System Sorting Test (D-KEFS ST) to obtain a more comprehensive ...
Alice Riccardi, Marco Puthenparampil, Francesca Rinaldi, Mario Ermani, Paola Perini, Paolo Gallo   +5 more
doaj   +1 more source

FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee, Jeffrey Lambe, Scott Johnson, Akua Abrah, Jennifer Bullen, Jeffrey A. Cohen, Tatchaporn Ongphichetmetha, Amy Kunchok   +7 more
wiley   +1 more source

Spatial constraints and cognitive fatigue affect motor imagery of walking in people with multiple sclerosis

Scientific Reports, 2020
Motor imagery (MI) is the mental simulation of an action without any overt motor execution. Interestingly, a temporal coupling between durations of real and imagined movements, i.e., the so-called isochrony principle, has been demonstrated in healthy ...
Jessica Podda, Ludovico Pedullà, Margherita Monti Bragadin, Elisa Piccardo, Mario Alberto Battaglia, Giampaolo Brichetto, Marco Bove, Andrea Tacchino   +7 more
doaj   +1 more source

Evaluation of cognitive assessment and cognitive intervention for people with multiple sclerosis

, 2002
Objectives: Cognitive problems in multiple sclerosis are common but any possible benefits of treatment remain uncertain. The aim of the study was to evaluate the benefits of providing a psychology service, including cognitive assessment and intervention,
Weyman, N., Blumhardt, L. D., Blumhardt, L.D., Harding, J., Lincoln, N. B., Dent, A., Nicholl, C., Lincoln, N.B., Playford, E.D., Playford, E. Diane   +9 more
core   +1 more source

Combining tractography and cortical measures to test system-specific hypotheses in multiple sclerosis. [PDF]

, 2010
The objective was to test three motor system-specific hypotheses in multiple sclerosis patients: (i) corticospinal tract and primary motor cortex imaging measures differ between multiple sclerosis patients and controls; (ii) in patients, these measures ...
Ciccarelli, Olga, Thompson, Alan J, Gorgoraptis, Nikos, Wheeler-Kingshott, Claudia AM, Altmann, Daniel R, Jenkins, Thomas M, Miller, David H   +6 more
core   +1 more source