Results 81 to 90 of about 6,788,532 (255)

Socioeconomic status of the elderly MS population compared to the general population: a nationwide Danish matched cross-sectional study

Frontiers in Neurology, 2023
Introduction/objectivesMultiple sclerosis (MS) leads to physical and cognitive disability, which in turn impacts the socioeconomic status of the individual.
Malthe Faurschou Wandall-Holm, Rolf Pringler Holm, Luigi Pontieri, Finn Sellebjerg, Melinda Magyari, Melinda Magyari   +5 more
doaj   +1 more source

A Case of Multiple Sclerosis Presenting as Eight and Half Syndrome. [PDF]

, 2013
Multiple sclerosis (MS) is a chronic disease characterized by inflammation, demyelination, gliosis (scarring), and neuronal loss; the course can be relapsing-remitting or progressive.
Kaushik, M, Mahajan, SK, Raghav, S, Raina, R, Sharathbabu, NM   +4 more
core  

Anger, Quality of Life and Mood in Multiple Sclerosis [PDF]

, 2015
This research was funded by The Multiple Sclerosis Society (UK).Peer reviewedPublisher ...
Cooper, Clare L, Hosie, Judith A, Laing, Christianne M, Phillips, Louise H, Summers, Fiona   +4 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

The effects of a 12-week leisure centre-based, group exercise intervention for people moderately affected with multiple sclerosis: a randomized controlled pilot study [PDF]

, 2011
<b>Objective:</b> To establish the effects of a 12-week, community-based group exercise intervention for people moderately affected with multiple sclerosis. <b>Design:</b> Randomised controlled pilot trial. <b>Setting:</
Learmonth, Y.C., Mattison, P., McFadyen, A.K., Miller, L., Paul, L.   +4 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Efficacy of intrathecal mesenchymal stem cell-neural progenitor therapy in progressive MS: results from a phase II, randomized, placebo-controlled clinical trial

Stem Cell Research & Therapy
Background Mesenchymal stem cell-neural progenitors (MSC-NPs) are a bone marrow mesenchymal stem cell (MSC)-derived ex vivo manipulated cell product with therapeutic potential in multiple sclerosis (MS).
Violaine K. Harris, James Stark, Armistead Williams, Morgan Roche, Michaela Malin, Anjali Kumar, Alyssa L. Carlson, Cara Kizilbash, Jaina Wollowitz, Caroline Andy, Linda M. Gerber, Saud A. Sadiq   +11 more
doaj   +1 more source

Inflammaging markers characteristic of advanced age show similar levels with frailty and dependency

Scientific Reports, 2021
The improvement of life quality and medical advances has resulted in increased life expectancy. Despite this, health status commonly worsens in the last years of life.
Ainhoa Alberro, Andrea Iribarren-Lopez, Matías Sáenz-Cuesta, Ander Matheu, Itziar Vergara, David Otaegui   +5 more
doaj   +1 more source

Psychiatric manifestations of multiple sclerosis and acute disseminated encephalomyelitis [PDF]

, 2006
It is unusual for acute disseminated encephalomyelitis and multiple sclerosis to present as purely psychiatric disorders. We report five patients with such demyelinating diseases and symptoms of psychosis, depression or anxiety.
Brinar, Marko, Brinar, Vesna V., Habek, Mario, Poser, Charles M.   +3 more
core   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source