Results 201 to 210 of about 752,420 (346)

Consideration of Multiple Sclerosis in Relation to the Auto-Immunity Process [PDF]

, 1961
C. E. Lumsden
openalex   +1 more source

A Machine‐Learning Approach Identifies Rejuvenating Interventions in the Human Brain

Advanced Science, EarlyView.
Rising life expectancy increases the incidence of age‐related neurodegeneration. Reverting brain aging through effective rejuvenation strategies constitutes a promising strategy to counteract these disorders and restore brain function. This study uses a brain‐specific transcriptional aging clock to screen over 43 000 perturbation profiles, identifying ...
Guillem Santamaria, Cristina Iglesias, Sascha Jung, Javier Arcos Hodar, Ruben Nogueiras, Antonio del Sol   +5 more
wiley   +1 more source

Hypoxia in multiple sclerosis. [PDF]

Redox Biol
Burtscher J, Motl RW, Berek K, Ehrenreich H, Kopp M, Hohenauer E.   +5 more
europepmc   +1 more source

Childhood multiple sclerosis with psychotic manifestations. [PDF]

, 1969
Luis F. Salguero, Hideo H. Itabashi, Nelly Gutiérrez   +2 more
openalex   +1 more source

SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy

Advanced Science, EarlyView.
During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong, Guangyu Liang, Huimin Yu, Jiaqi Li, Ruohong Wang, Xiaohong Ma, Ziqing Zhou, Yin Zhao, Fei Sun, Xufang Sun   +9 more
wiley   +1 more source

Comparative effectiveness of teriflunomide and ocrelizumab on smoldering activity in multiple sclerosis: an observational study in the Swiss Multiple Sclerosis Cohort. [PDF]

J Neurol
Cagol A, Schaedelin S, Ocampo-Pineda M, Benkert P, Melie-Garcia L, Luchetti L, Yaldizli Ö, Oechtering J, D'Souza M, Fischer-Barnicol B, Müller S, Finkener S, Vehoff J, Disanto G, Chan A, Pot C, Zecca C, Derfuss T, Lieb JM, Diepers M, Wagner F, Du Pasquier R, Lalive PH, Pravatà E, Kim OC, Hoepner R, Roth P, Gobbi C, Leppert D, Battaglini M, Kappos L, Sormani MP, Kuhle J, Granziera C, Swiss MS Cohort.   +34 more
europepmc   +1 more source

THERAPEUTIC TRIALS IN MULTIPLE SCLEROSIS: PRELIMINARY REPORT ON EFFECTS OF INTRATHECAL INJECTION OF TUBERCULIN (P.P.D.) [PDF]

, 1961
Henry Miller, D. J. Newell, A Ridley, Kurt Schapira   +3 more
openalex   +1 more source

A Wearable AI‐Driven Mask with Humidity‐Sensing Respiratory Microphone for Non‐Vocal Communication

Advanced Science, EarlyView.
A wearable, plug‐and‐play respiratory microphone—featuring a gold nanoparticle‐based humidity sensor—facilitates voice‐free verbal communication for patients with impaired vocal fold function. Abstract Hoarseness and dysphonia caused by vocal cord conditions or laryngeal surgeries significantly hinder communication and quality of life.
Jianfei Wang, Hongyu Zhang, Xiaomin Wu, Mingyan Gao, He Wen, Zhibo Zhang, Kremena Makasheva, Wen Jung Li, Zuobin Wang   +8 more
wiley   +1 more source

Advancements in multiple sclerosis. [PDF]

Intern Med J
Montague T, Drummond J, Ng K, Parratt J.
europepmc   +1 more source

The relationship between enzyme activity and neuroglia in plaques of multiple sclerosis [PDF]

, 1963
M. Z. M. Ibrahim, C. W. M. Adams
openalex   +1 more source