Results 1 to 10 of about 421,641 (311)

Smouldering multiple sclerosis: the ‘real MS’

Therapeutic Advances in Neurological Disorders, 2022
Using a philosophical approach or deductive reasoning, we challenge the dominant clinico-radiological worldview that defines multiple sclerosis (MS) as a focal inflammatory disease of the central nervous system (CNS).
Gavin Giovannoni, Veronica Popescu, Jens Wuerfel, Kerstin Hellwig, Ellen Iacobaeus, Michael B. Jensen, José Manuel García-Domínguez, Livia Sousa, Nicola De Rossi, Raymond Hupperts, Giuseppe Fenu, Benedetta Bodini, Hanna-Maija Kuusisto, Bruno Stankoff, Jan Lycke, Laura Airas, Cristina Granziera, Antonio Scalfari   +17 more
doaj   +2 more sources

Vitamin D and Neurodegenerative Diseases Such as Multiple Sclerosis (MS), Parkinson’s Disease (PD), Alzheimer’s Disease (AD), and Amyotrophic Lateral Sclerosis (ALS): A Review of Current Literature [PDF]

Curr Nutr Rep
Savran Z, Baltaci S, Aladag T, Mogulkoc R, Baltaci A.   +4 more
europepmc   +3 more sources

NK Cells and Innate-Like T Cells After Autologous Hematopoietic Stem Cell Transplantation in Multiple Sclerosis

Frontiers in Immunology, 2021
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system, in which autoreactive T and B cells play important roles. Other lymphocytes such as NK cells and innate-like T cells appear to be involved as well.
Josefine Ruder, Jordan Rex, Simon Obahor, María José Docampo, Antonia M. S. Müller, Urs Schanz, Ilijas Jelcic, Roland Martin   +7 more
doaj   +1 more source

Safety of the BNT162b2 COVID‐19 vaccine in multiple sclerosis (MS): Early experience from a tertiary MS center in Israel

European Journal of Neurology, 2021
Although the COVID‐19 vaccines are currently recommended for people with multiple sclerosis (MS), the fact that they were not specifically tested in people with MS raises uncertainty regarding their safety in this population.
I. Lotan, Adi Wilf-Yarkoni, Yitzhak Friedman, H. Stiebel-Kalish, I. Steiner, M. Hellmann   +5 more
semanticscholar   +1 more source

Enhancing mitochondrial activity in neurons protects against neurodegeneration in a mouse model of multiple sclerosis

eLife, 2021
While transcripts of neuronal mitochondrial genes are strongly suppressed in central nervous system inflammation, it is unknown whether this results in mitochondrial dysfunction and whether an increase of mitochondrial function can rescue ...
Sina C Rosenkranz, Artem A Shaposhnykov, Simone Träger, Jan Broder Engler, Maarten E Witte, Vanessa Roth, Vanessa Vieira, Nanne Paauw, Simone Bauer, Celina Schwencke-Westphal, Charlotte Schubert, Lukas Can Bal, Benjamin Schattling, Ole Pless, Jack van Horssen, Marc Freichel, Manuel A Friese   +16 more
doaj   +1 more source

Neutrophils: Underestimated Players in the Pathogenesis of Multiple Sclerosis (MS)

International Journal of Molecular Sciences, 2020
Neutrophils are the most abundant circulating and first-responding innate myeloid cells and have so far been underestimated in the context of multiple sclerosis (MS).
Mirre De Bondt, N. Hellings, G. Opdenakker, S. Struyf   +3 more
semanticscholar   +1 more source

Improving Glucocorticoid Sensitivity of Brain-Homing CD4+ T Helper Cells by Steroid Hormone Crosstalk

Frontiers in Immunology, 2022
In early multiple sclerosis (MS), an IFN-γhighGM-CSFhighIL-17low CD4+ T-cell subset termed T helper 17.1 (Th17.1) reveals enhanced capacity to infiltrate the central nervous system. Th17.1 cells express high levels of multidrug resistance protein 1 (MDR1)
Steven C. Koetzier, Steven C. Koetzier, Jamie van Langelaar, Jamie van Langelaar, Annet F. Wierenga-Wolf, Annet F. Wierenga-Wolf, Marie-José Melief, Marie-José Melief, Kim Pol, Kim Pol, Suzanne Musters, Suzanne Musters, Erik Lubberts, Willem A. Dik, Willem A. Dik, Joost Smolders, Joost Smolders, Joost Smolders, Joost Smolders, Marvin M. van Luijn, Marvin M. van Luijn   +20 more
doaj   +1 more source

Rising prevalence of multiple sclerosis worldwide: Insights from the Atlas of MS, third edition

Multiple Sclerosis, 2020
Background: High-quality epidemiologic data worldwide are needed to improve our understanding of disease risk, support health policy to meet the diverse needs of people with multiple sclerosis (MS) and support advocacy efforts.
Clare Walton, Rachel King, Lindsay Rechtman, W. Kaye, E. Leray, R. Marrie, N. Robertson, N. La Rocca, B. Uitdehaag, I. van der Mei, M. Wallin, A. Helme, Ceri Angood Napier, N. Rijke, P. Baneke   +14 more
semanticscholar   +1 more source

Advanced imaging for multiple sclerosis (ORP-14) [PDF]

Neurology Letters, 2023
This study focuses on the use of advanced imaging techniques for the assessment of multiple sclerosis (MS). The objective is to explore the potential of these imaging modalities in providing valuable insights into the pathophysiology and characterization
Elnaz Asadollahzadeh
doaj  

Podcast on the Challenges and Recommendations to Address Unmet Needs in MS for LGBTQ+ Populations in the United States

Neurology and Therapy, 2023
In general, individuals who are lesbian, gay, bisexual, transgender, queer or questioning, plus other identities (LGBTQ+) living with multiple sclerosis (MS) have less favorable healthcare experiences and poorer overall health than cisgendered ...
William L. Conte, Mark Cascione, Amy B. Sullivan   +2 more
doaj   +1 more source