Results 131 to 140 of about 1,008,958 (324)
CONSENT: Scalable long read self-correction and assembly polishing with multiple sequence alignment [PDF]
, 2019 Pierre Morisse +4 more
openalex +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Improved mammalian family phylogeny using gap-rare multiple sequence alignment: A timetree of extant placentals and marsupials. [PDF]
Zool Res, 2023 Liu GM +16 more
europepmc +1 more source
TCS: a web server for multiple sequence alignment evaluation and phylogenetic reconstruction: Figure 1. [PDF]
, 2015 Jia‐Ming Chang +4 more
openalex +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Study of the error correction capability of multiple sequence alignment algorithm (MAFFT) in DNA storage. [PDF]
BMC Bioinformatics, 2023 Xie R, Zan X, Chu L, Su Y, Xu P, Liu W.
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Accuracy of multiple sequence alignment methods in the reconstruction of transposable element families. [PDF]
NAR Genom Bioinform, 2022 Hubley R, Wheeler TJ, Smit AFA.
europepmc +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source