Results 161 to 170 of about 1,261,273 (206)

Evaluating the Accuracy and Efficiency of Multiple Sequence Alignment Methods

open access: yesEvolutionary Bioinformatics, 2014
Muhammad Tariq Pervez   +10 more
doaj  

Multiple sequence alignment

Current Opinion in Structural Biology, 2006
Multiple sequence alignments are an essential tool for protein structure and function prediction, phylogeny inference and other common tasks in sequence analysis. Recently developed systems have advanced the state of the art with respect to accuracy, ability to scale to thousands of proteins and flexibility in comparing proteins that do not share the ...
Robert C. Edgar, Serafim Batzoglou
openaire   +4 more sources

Multiple Sequence Alignment [PDF]

open access: possible, 2016
The increasing importance of Next Generation Sequencing (NGS) techniques has highlighted the key role of multiple sequence alignment (MSA) in comparative structure and function analysis of biological sequences. MSA often leads to fundamental biological insight into sequence-structure-function relationships of nucleotide or protein sequence families ...
K. Anton Feenstra   +5 more
openaire   +3 more sources

Multiple Sequence Alignment

2003
Publisher Summary This chapter discusses various aspects of multiple sequence alignment. Dynamic programming can be generalized to more than two sequences where one finds the multiple alignments with the best score according to the scoring scheme. Gaps are scored according to their length and the number of sequences that they occur in and the method ...
Desmond G. Higgens, William R. Taylor
openaire   +5 more sources

Multiple sequence alignment

Journal of Molecular Biology, 1986
A method has been developed for aligning segments of several sequences at once. The number of search steps depends only polynomially on the number of sequences, instead of exponentially, because most alignments are rejected without being evaluated explicitly. A data structure herein called the "heap" facilitates this process.
David J. Bacon, Wayne F. Anderson
openaire   +3 more sources

An Overview of Multiple Sequence Alignment

Current Protocols in Bioinformatics, 2003
AbstractMultiple sequence alignment is perhaps the most commonly applied bioinformatics technique. It often leads to fundamental biological insight into sequence‐structure‐function relationships of nucleotide or protein sequence families. In this unit, an overview of multiple sequence alignment techniques is presented, covering a history of nearly 30 ...
Jens Kleinjung   +2 more
openaire   +3 more sources

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