Results 161 to 170 of about 6,883,088 (299)

Divide-and-Conquer Multiple Sequence Alignment

, 1997
Contents 1 Introduction 1 1.1 Preliminaries . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 1.2 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 1.3 Acknowledgements . . . . . . . . . . . . . . . . . . . . .
Gerhard Sagerer, Jens Stoye, Technischen Fakultat, Ipke Wachsmuth, Doktors Der Naturwissenschaften, Helge Ritter, Abteilung Informationstechnik, Impressum Herausgeber, Alois Knoll, Robert Giegerich, Peter Ladkin, Bielefeld Im Januar   +11 more
core  

Study of the error correction capability of multiple sequence alignment algorithm (MAFFT) in DNA storage. [PDF]

BMC Bioinformatics, 2023
Xie R, Zan X, Chu L, Su Y, Xu P, Liu W.
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Accuracy of multiple sequence alignment methods in the reconstruction of transposable element families. [PDF]

NAR Genom Bioinform, 2022
Hubley R, Wheeler TJ, Smit AFA.
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

MAGUS: Multiple sequence Alignment using Graph clUStering. [PDF]

Bioinformatics, 2021
Smirnov V, Warnow T.
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

MAGUS+eHMMs: improved multiple sequence alignment accuracy for fragmentary sequences. [PDF]

Bioinformatics, 2022
Shen C, Zaharias P, Warnow T.
europepmc   +1 more source