Results 31 to 40 of about 419,969 (204)
A tool for multiple sequence alignment. [PDF]
Proceedings of the National Academy of Sciences, 1989 Multiple sequence alignment can be a useful technique for studying molecular evolution and analyzing sequence-structure relationships. Until recently, it has been impractical to apply dynamic programming, the most widely accepted method for producing pairwise alignments, to comparisons of more than three sequences.
John Kececioglu +2 more
openaire +3 more sources
, 2008 Multiple sequence alignment (MSA) has assumed a key role in comparative structure and function analysis of biological sequences. It often leads to fundamental biological insight into sequence-structure-function relationships of nucleotide or protein sequence families.
Pirovano, W., Heringa, J.
openaire +4 more sources
Scaling statistical multiple sequence alignment to large datasets
BMC Genomics, 2016 Background Multiple sequence alignment is an important task in bioinformatics, and alignments of large datasets containing hundreds or thousands of sequences are increasingly of interest.
Michael Nute, Tandy Warnow
doaj +1 more source
BMC Bioinformatics, 2010 Background Large nucleotide sequence datasets are becoming increasingly common objects of comparison. Complete bacterial genomes are reported almost everyday. This creates challenges for developing new multiple sequence alignment methods.
Kryukov Kirill, Saitou Naruya
doaj +1 more source
Protein Multiple Sequence Alignment [PDF]
, 2008 Protein sequence alignment is the task of identifying evolutionarily or structurally related positions in a collection of amino acid sequences. Although the protein alignment problem has been studied for several decades, many recent studies have demonstrated considerable progress in improving the accuracy or scalability of multiple and pairwise ...
Kazutaka Katoh, Chuong B. Do
openaire +3 more sources
Current Trends and Ongoing Progress in the Computational Alignment of Biological Sequences
IEEE Access, 2019 The computational techniques for nucleic acid and protein sequence comparison reduce the extensive burden of molecular biologists. The sequence alignment is one of the main research areas in bioinformatics, and comparative genomics and proteomics lead us
Muhammad Ishaq +3 more
doaj +1 more source
BMC Bioinformatics, 2020 Background Given a binary tree T $\mathcal {T}$ of n leaves, each leaf labeled by a string of length at most k, and a binary string alignment function ⊗, an implied alignment can be generated to describe the alignment of a dynamic homology for T ...
Alex J. Washburn, Ward C. Wheeler
doaj +1 more source
The Multiple Sequence Alignment Problem in Biology [PDF]
SIAM Journal on Applied Mathematics, 1988 Summary: The study and comparison of sequences of characters from a finite alphabet is relevant to various areas of science, notably molecular biology. The measurement of sequence similarity involves the consideration of the different possible sequence alignments in order to find an optimal one for which the ``distance'' between sequences is minimum ...
Carrillo, Humberto, Lipman, David
openaire +3 more sources
Parallel progressive multiple sequence alignment on reconfigurable meshes
BMC Genomics, 2011 Background One of the most fundamental and challenging tasks in bio-informatics is to identify related sequences and their hidden biological significance.
Nguyen Ken D, Pan Yi, Nong Ge
doaj +1 more source
A multiple sequence alignment program
Nucleic Acids Research, 1986 A program is described for simultaneously aligning two or more molecular sequences which is based on first finding common segments above a specified length and then piecing these together to maximize an alignment scoring function. Optimal as well as near-optimal alignments are found, and there is also provided a means for randomizing the given ...
Eric M. Sobel, Hugo M. Martinez
openaire +4 more sources