Results 41 to 50 of about 483,132 (293)

Fast and sensitive multiple alignment of large genomic sequences

, 2003
Brudno M, Chapman M, Göttgens B, Batzoglou S, Morgenstern B. Fast and sensitive multiple alignment of large genomic sequences. BMC Bioinformatics.
Brudno, Michael, Batzoglou, S., Chapman, Mark A., Göttgens, Berthold, Batzoglou, Serafim, Morgenstern, Burkhard, Gottgens, B., Chapman, Michael, Berthold Göttgens, Brudno, M., Burkhard Morgenstern, Michael Chapman, Michael Brudno, Serafim Batzoglou   +13 more
core   +1 more source

MCALIGN2: Faster, accurate global pairwise alignment of non-coding DNA sequences based on explicit models of indel evolution [PDF]

, 2006
Background Non-coding DNA sequences comprise a very large proportion of the total genomic content of mammals, most other vertebrates, many invertebrates, and most plants. Unraveling the functional significance of non-coding DNA depends on how well we are
Johnson Toby, Wang Jun, Johnson, Toby, Keightley Peter D, Keightley, Peter, Wang, Jun   +5 more
core   +1 more source

MergeAlign: improving multiple sequence alignment performance by dynamic reconstruction of consensus multiple sequence alignments

BMC Bioinformatics, 2012
Background The generation of multiple sequence alignments (MSAs) is a crucial step for many bioinformatic analyses. Thus improving MSA accuracy and identifying potential errors in MSAs is important for a wide range of post-genomic research.
Collingridge Peter W, Kelly Steven
doaj   +1 more source

QAlign: quality-based multiple alignments with dynamic phylogenetic analysis

, 2003
Sammeth M, Rothgänger J, Esser W, Albert J, Stoye J, Harmsen D. QAlign: quality-based multiple alignments with dynamic phylogenetic analysis. BIOINFORMATICS.
Esser, Wolfram, Sammeth, Michael, Stoye, Jens ; https://orcid.org/, Rothgänger, Jörg, Albert, Jürgen, Harmsen, Dag   +5 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

MISHIMA - a new method for high speed multiple alignment of nucleotide sequences of bacterial genome scale data

BMC Bioinformatics, 2010
Background Large nucleotide sequence datasets are becoming increasingly common objects of comparison. Complete bacterial genomes are reported almost everyday. This creates challenges for developing new multiple sequence alignment methods.
Kryukov Kirill, Saitou Naruya
doaj   +1 more source

Multiple sequence alignment by consensus [PDF]

Nucleic Acids Research, 1986
An algorithm for multiple sequence alignment is given that matches words of length and degree of mismatch chosen by the user. The alignment maximizes an alignment scoring function. The method is based on a novel extension of our consensus sequence methods.
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Three-Way Alignment Improves Multiple Sequence Alignment of Highly Diverged Sequences

Algorithms
The standard approach for constructing a phylogenetic tree from a set of sequences consists of two key stages. First, a multiple sequence alignment (MSA) of the sequences is computed.
Mahbubeh Askari Rad, Alibek Kruglikov, Xuhua Xia   +2 more
doaj   +1 more source

Current Trends and Ongoing Progress in the Computational Alignment of Biological Sequences

IEEE Access, 2019
The computational techniques for nucleic acid and protein sequence comparison reduce the extensive burden of molecular biologists. The sequence alignment is one of the main research areas in bioinformatics, and comparative genomics and proteomics lead us
Muhammad Ishaq, Asfandyar Khan, Majid Khan, Muhammad Imran   +3 more
doaj   +1 more source