Results 41 to 50 of about 453,572 (256)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Scenario forecasting methods have been widely studied in recent years to cope with the wind power uncertainty problem. The main difficulty of this problem is to accurately and comprehensively reflect the time-series characteristics and spatial-temporal ...
Qingyu Tu +7 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Automated Detection of Paroxysmal Atrial Fibrillation Using an Information-Based Similarity Approach
Atrial fibrillation (AF) is an abnormal rhythm of the heart, which can increase heart-related complications. Paroxysmal AF episodes occur intermittently with varying duration.
Xingran Cui +5 more
doaj +1 more source
INTEGRATION OF TERRESTRIAL LASER SCANNING POINTS AND 2D FLOOR PLANS BASED ON MAXIMUM SEQUENTIAL SIMILARITY [PDF]
This paper presents a Maximum Sequential Similarity Reasoning (MSSR) algorithm based method for co-registration of 3D TLS data and 2D floor plans. The co-registration consists of two tasks: estimating a transformation between the two datasets and finding
L. Wang, G. Sohn
doaj +1 more source
Identifying Actionable Serial Correlations in Financial Markets
Financial markets are complex systems where information processing occurs at multiple levels. One signature of this information processing is the existence of recurrent sequences.
Siew Ann Cheong +6 more
doaj +1 more source
We give a review of recent results on equiconvergence of expansions in multiple trigonometric Fourier series and Fourier integral in the case of summation over rectangles.
Igor L. Bloshanskii, Denis A. Grafov
openaire +2 more sources
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Mahler series with multiplicative coefficient sequences
We prove that every Mahler series, over a field of characteristic $0$, with multiplicative coefficients is regular in the sense of Allouche and Shallit. We also obtain an explicit characterization of such series. This yields a joint extension of the characterization of rational series with multiplicative coefficients (by Bézivin and Bell--Bruin--Coons)
Bell, Jason, Smertnig, Daniel
openaire +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source

