Results 51 to 60 of about 483,582 (250)
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Pseudostarlikeness and Pseudoconvexity of Multiple Dirichlet Series
Universal Journal of Mathematics and Applications, 2023 Let $p\in {\Bbb N}$, $s=(s_1,\ldots,s_p)\in {\Bbb C}^p$, $h=(h_1,\ldots,h_p)\in {\Bbb R}^p_+$, $(n)=(n_1,\ldots,n_p)\in {\Bbb N}^p$ and the sequences $\lambda_{(n)}=(\lambda^{(1)}_{n_1},\ldots,\lambda^{(p)}_{n_p})$ are such that $0<\lambda^{(j)}_1 ...
Myroslav Sheremeta
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
STUDENT\u27S MISCONCEPTIONS OF SEQUENCES AND SERIES IN SECOND SEMESTER CALCULUS [PDF]
, 2017 Little is known about the difficulty students have with sequences and series in second semester calculus courses. In my dissertation, I investigate the misconceptions students had about sequences and series as they worked through problems typically seen
Earls, David
core +1 more source
IEEE Access, 2018 The energy consumption by non-residential consumers in China accounts for a significant proportion of the total energy consumption in the society. Thus, accurate non-residential load forecasting plays an increasingly essential role in the future grid ...
Runhai Jiao +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A novel fast target tracking method for UAV aerial image
Open Physics, 2017 Unmanned aerial vehicles (UAV) are able to achieve autonomous flight without drivers, and UAV has been a key tool to extract space data. Therefore, how to detect the trajectories of targets from UAV aerial image sequences is of great importance.
Jianfang Liu, Hao Zheng, Jingli Gao
doaj +1 more source
, 2022 The SpTransformer (SpTrf) gene family encodes a set of proteins that function in the sea urchin immune system. The gene sequences have a series of internal repeats in a mosaic pattern that is characteristic of this family.
Megan A. Barela Hudgell (11701967) +1 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Automated Detection of Paroxysmal Atrial Fibrillation Using an Information-Based Similarity Approach
Entropy, 2017 Atrial fibrillation (AF) is an abnormal rhythm of the heart, which can increase heart-related complications. Paroxysmal AF episodes occur intermittently with varying duration.
Xingran Cui +5 more
doaj +1 more source