Results 61 to 70 of about 1,208,960 (264)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Identifying Actionable Serial Correlations in Financial Markets

Frontiers in Applied Mathematics and Statistics, 2021
Financial markets are complex systems where information processing occurs at multiple levels. One signature of this information processing is the existence of recurrent sequences.
Siew Ann Cheong, Siew Ann Cheong, Yann Wei Lee, Ying Ying Li, Jia Qing Lim, Jiok Duan Jadie Tan, Xin Ping Joan Teo   +6 more
doaj   +1 more source

Listen, Attend, and Walk: Neural Mapping of Navigational Instructions to Action Sequences

, 2015
We propose a neural sequence-to-sequence model for direction following, a task that is essential to realizing effective autonomous agents. Our alignment-based encoder-decoder model with long short-term memory recurrent neural networks (LSTM-RNN ...
Bansal, Mohit, Mei, Hongyuan, Walter, Matthew R.   +2 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

INTEGRATION OF TERRESTRIAL LASER SCANNING POINTS AND 2D FLOOR PLANS BASED ON MAXIMUM SEQUENTIAL SIMILARITY [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2012
This paper presents a Maximum Sequential Similarity Reasoning (MSSR) algorithm based method for co-registration of 3D TLS data and 2D floor plans. The co-registration consists of two tasks: estimating a transformation between the two datasets and finding
L. Wang, G. Sohn
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

AMDCnet: attention-gate-based multi-scale decomposition and collaboration network for long-term time series forecasting

Frontiers in Artificial Intelligence
IntroductionTime series analysis plays a critical role in various applications, including sensor data monitoring, weather forecasting, economic predictions, and network traffic management. While traditional methods primarily focus on modeling time series
Shikang Hou, Song Sun, Tao Yin, Zhibin Zhang, Meng Yan   +4 more
doaj   +1 more source

A Visual Analytics Approach for User Behaviour Understanding through Action Sequence Analysis [PDF]

, 2017
Analysis of action sequence data provides new opportunities to understand and model user behaviour. Such data are often in the form of timestamped and labelled series of atomic user actions. Cyber security is one of the domains that show the value of the
Andrienko, G., Andrienko, N., Nguyen, P., Thonnard, O., Turkay, C.   +4 more
core  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Entropy of Entropy: Measurement of Dynamical Complexity for Biological Systems

Entropy, 2017
Healthy systems exhibit complex dynamics on the changing of information embedded in physiologic signals on multiple time scales that can be quantified by employing multiscale entropy (MSE) analysis.
Chang Francis Hsu, Sung-Yang Wei, Han-Ping Huang, Long Hsu, Sien Chi, Chung-Kang Peng   +5 more
doaj   +1 more source