Results 41 to 50 of about 179,091 (292)

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Receding Horizon Trajectory Generation of Stratospheric Airship in Low-Altitude Return Phase

Aerospace, 2022
The contribution of this paper is the proposal of a new receding horizon trajectory generation method for stratospheric airships’ return phase. Since the energy consumption, wind field and path constraints are restrictions during the return phase of ...
Yuhao Jing, Yang Wu, Jiwei Tang, Pingfang Zhou, Dengping Duan   +4 more
doaj   +1 more source

Solving nonlinear system of third-order boundary value problems using block method [PDF]

, 2014
In this paper, we propose an algorithm of two-point block method to solve the nonlinear system of third-order boundary value problems directly. The proposed method is presented in a simple form of Adams type and two approximate solutions will be obtained
Abdul Majid, Zanariah, Ismail, Fudziah, Othman, Khairil Iskandar, Phang, Pei See, Suleiman, Mohamed   +4 more
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Period-Multiplying Bifurcations in the Gravitational Field of Asteroids

Aerospace
Periodic orbit families around asteroids serve as potential trajectories for space probes, mining facilities, and deep space stations. Bifurcations of these families provide additional candidate orbits for efficient trajectory design around asteroids ...
P. Rishi Krishna, Joel George Manathara
doaj   +1 more source

Evaluation of Close-Range Photogrammetry Image Collection Methods for Estimating Tree Diameters

ISPRS International Journal of Geo-Information, 2018
The potential of close-range photogrammetry (CRP) to compete with terrestrial laser scanning (TLS) to produce dense and accurate point clouds has increased in recent years.
Martin Mokroš, Xinlian Liang, Peter Surový, Peter Valent, Juraj Čerňava, František Chudý, Daniel Tunák, Šimon Saloň, Ján Merganič   +8 more
doaj   +1 more source

Triple Solutions and Stability Analysis of Micropolar Fluid Flow on an Exponentially Shrinking Surface

Crystals, 2020
In this article, we reconsidered the problem of Aurangzaib et al., and reproduced the results for triple solutions. The system of governing equations has been transformed into the system of non-linear ordinary differential equations (ODEs) by using ...
Liaquat Ali Lund, Zurni Omar, Ilyas Khan, Dumitru Baleanu, Kottakkaran Sooppy Nisar   +4 more
doaj   +1 more source

What Do Large Language Models Know About Materials?

Advanced Engineering Materials, EarlyView.
If large language models (LLMs) are to be used inside the material discovery and engineering process, they must be benchmarked for the accurateness of intrinsic material knowledge. The current work introduces 1) a reasoning process through the processing–structure–property–performance chain and 2) a tool for benchmarking knowledge of LLMs concerning ...
Adrian Ehrenhofer, Thomas Wallmersperger, Gianaurelio Cuniberti   +2 more
wiley   +1 more source

A kinematical approach to gravitational lensing using new formulae for refractive index and acceleration

, 2010
This paper uses the Schwarzschild metric to derive an effective refractive index and acceleration vector that account for relativistic deflection of light rays, in an otherwise classical kinematic framework.
Boroson, Capozziello, Carroll, Ellis, Kenyon, L. K. Forbes, Mao, Misner, Newton, P. D. Jarvis, Paczynski, Perkins, S. J. Walters, Schneider, Shapiro, Sumi, Wambsganss, Weinberg, Zabel   +18 more
core   +1 more source