Results 61 to 70 of about 2,232,801 (311)
Medical Statistics – Mathematics or Oracle? Farewell Lecture
GMS Medizinische Informatik, Biometrie und Epidemiologie, 2005 Certainty is rare in medicine. This is a direct consequence of the individuality of each and every human being and the reason why we need medical statistics. However, statistics have their pitfalls, too. Fig. 1 shows that the suicide rate peaks in youth,
Gaus, Wilhelm
doaj
Detecting multiple associations in genome-wide studies
Human Genomics, 2006 Recent developments in the statistical analysis of genome-wide studies are reviewed. Genome-wide analyses are becoming increasingly common in areas such as scans for disease-associated markers and gene expression profiling.
Dudbridge Frank +2 more
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Discrepancies in Immunohaematological Testing-Importance of Use of Multiple Modalities of Testing [PDF]
National Journal of Laboratory Medicine, 2019 Two cases are being reported here which shows that in case of immuno-hematological discrepancies, the standard mode of testing should always be supplemented by additional methods to gain an insight into further work-up.
Soumee Banerjee +3 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Increasing power of robust test through pre-testing in multiple regression model [PDF]
, 2010 In this paper, we define (i) unrestricted (UT), (ii) restricted (RT) and (iii)pre-test (PTT) tests for testing the significance of a subset of the parameters of a multiple regression model when the remaining parameters are (i) completely unspecified ...
Yunus, Rossita M., Khan, Shahjahan
core
, 2001 Aims to commend SEM ( structural equation modeling) that excels beyond multiple regression which is a popular statistical technique to test the relationships of independent and dependent variables, in expanding the explanatory ability and statistical ...
Cheng, Eddie W. L.
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Statistical Theory and Related Fields, 2017 This paper focuses on the influence of a misspecified covariance structure on false discovery rate for the large-scale multiple testing problem. Specifically, we evaluate the influence on the marginal distribution of local false discovery rate statistics,
Ye Liang, Joshua D. Habiger, Xiaoyi Min
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