Results 61 to 70 of about 482,148 (298)

Nonlinearities in Cross-Country Growth Regressions: A Bayesian Averaging of Thresholds (BAT) Approach

open access: yes, 2007
We propose a Bayesian Averaging of Thresholds (BAT) approach for assessing the existence and quantifying the effect of threshold effects in cross-country growth regressions in the presence of model uncertainty.

core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Too low to be true: the use of minimum thresholds to fight tax evasion [PDF]

open access: yes, 2010
The enforcement of compliance with tax regulation is a complex task. This is particularly the case when the administrative capacity of the tax authority is low, as it often happens in developing and transition countries.
Tonin, Mirco
core  

Dynamic Itemset Mining Under Multiple Support Thresholds

open access: yes, 2016
Handling dynamic aspect of databases and multiple support threshold requirements of items are two important challenges of frequent itemset mining algorithms.
Ergenç, Belgin, Abuzayed, Nourhan
core   +1 more source

Empirical approach to threshold determination for the delineation of built-up areas with road network data.

open access: yesPLoS ONE, 2018
Various approaches have been proposed to address the delineation of built-up areas for a wide range of applications. Recently developed approaches are based on the increasing availability of road network data.
Qi Zhou, Lei Guo
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Mining of high average-utility patterns with item-level thresholds

open access: yes, 2019
In this paper, we introduce a level-wise algorithm named High Average-Utility Itemset Mining with Multiple Minimum Average-Utility threshold (HAUIM-MMAU), which relies on a novel transaction-maximum utility downward closure (TMUDC) property and a concept
Zhang, Ji   +4 more
core   +1 more source

T1- Thresholds in Black Holes Increase Clinical-Radiological Correlation in Multiple Sclerosis Patients.

open access: yesPLoS ONE, 2015
BackgroundMagnetic Resonance Imaging (MRI) is an established tool in diagnosing and evaluating disease activity in Multiple Sclerosis (MS). While clinical-radiological correlations are limited in general, hypointense T1 lesions (also known as Black Holes
Christian Thaler   +8 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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