Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Airborne disease transmission during indoor gatherings over multiple time scales: Modeling framework and policy implications. [PDF]
Proc Natl Acad Sci U S A, 2023 Dixit AK +4 more
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The NAO Variability Prediction and Forecasting with Multiple Time Scales Driven by ENSO Using Machine Learning Approaches. [PDF]
Comput Intell Neurosci, 2022 Mu B, Li J, Yuan S, Luo X.
europepmc +1 more source
Satellite attitude prediction by multiple time scales method [PDF]
, 1975 An investigation is made of the problem of predicting the attitude of satellites under the influence of external disturbing torques. The attitude dynamics are first expressed in a perturbation formulation which is then solved by the multiple scales ...
Tao, Y. C., Ramnath, R.
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Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
MULTIPLE LEBESGUE INTEGRATION ON TIME SCALES
, 2008 We study the process of multiple Lebesgue integration on time scales. The relationship of the Riemann and the Lebesgue multiple integrals is investigated. Copyright © 2006 M. Bohner and G. Sh. Guseinov.
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Data-Driven Proactive Early Warning of Grid Congestion Probability Based on Multiple Time Scales
EnergiesWith the development of new power systems, the increased interactive demand on the load side, and the high proportion of renewable energy sources on the power side, grid congestion problems due to increased system uncertainty are becoming more frequent ...
Haobo Fu +7 more
doaj +1 more source
Alteration in Functional Magnetic Resonance Imaging Signal Complexity Across Multiple Time Scales in Patients With Migraine Without Aura. [PDF]
Front Neurosci, 2022 Wang X +13 more
europepmc +1 more source