Results 101 to 110 of about 20,490,842 (288)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Multiple Time Scales and Longitudinal Measurements in Event History Analysis
, 2005 A general time-to-event data analysis known as event history analysis is considered. The focus is on the analysis of time-to-event data using Cox's regression model when the time to the event may be measured from different origins giving several ...
Danardono,
core +2 more sources
Multiple time scales method for a two dimensional system with distributed delays
Annals of the West University of Timisoara: Mathematics and Computer ScienceBuilding on the simplified mathematical model derived from the dynamics of the hypothalamic-pituitary-adrenal (HPA) axis, which describes the interactions between ACTH and cortisol through a system of differential equations with distributed delays, this ...
Matei Maria Roxana
doaj +1 more source
EnergiesThe “dual carbon” goal has made it a mainstream trend for new energy stations (NESs) and energy storage stations (ESSs) to jointly participate in market regulation.
Suwei Zhai +3 more
doaj +1 more source
Integrating multiple time-scales to advance relationship science
, 2023 It is widely acknowledged that social relationships unfold across multiple time-scales. For example, social interactions that take place over moments, hours, or days also shape relationship change and outcomes over months, years, and even decades. These
Benson, Lizbeth +5 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Two-time scales inner solutions and motion of a geostrophic vortex
, 1988 Based on the authors' previous work, in this paper the systematical analyses on the motion and the inner solutions of a geostrophic vortex have been presented by means of thematched asymptotic expansion method with multiple time scales (S/gh001/2 and α S/
凌国灿, Ting L(丁汝)
core +2 more sources
Slow-time acceleration for modeling multiple-time-scale problems
Journal of Computational Physics, 2010 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, FL 32611-6300, United States ( host institution ) +4 more
openaire +2 more sources
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Suicidal urges and attempted suicide at multiple time scales in borderline personality disorder. [PDF]
J Affect Disord, 2023 Kaurin A +3 more
europepmc +1 more source