Results 91 to 100 of about 28,735,040 (303)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Improper Integrals on Time Scales
, 2003 In this paper we study improper integrals on time scales. We also give some mean value theorems for integrals on time scales, which are used in the proof of an analogue of the classical Dirichlet-Abel test for improper ...
Guseinov, GS, Bohner, M
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Satellite attitude prediction by multiple time scales method [PDF]
, 1975 An investigation is made of the problem of predicting the attitude of satellites under the influence of external disturbing torques. The attitude dynamics are first expressed in a perturbation formulation which is then solved by the multiple scales ...
Tao, Y. C., Ramnath, R.
core
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
An IRT Analysis of Motive Questionnaires: The Unified Motive Scales [PDF]
, 2012 Multiple inventories claiming to assess the same explicit motive (achievement, power, or affiliation) show only mediocre convergent validity. In three studies (N = 1685) the structure, nomological net, and content coverage of multiple existing motive ...
Gerstenberg, Friederike X. R. +1 more
core +1 more source
and Adams–Bashforth method on time scales
, 2022 ERHAN, INCI M./0000-0001-6042-3695A recent study on the Taylor series method of second order and the trapezoidal rule for dynamic equations on time scales has been continued by introducing a derivation of the Taylor series method of arbitrary order p$$ p
Erhan, Inci M. +3 more
core +1 more source
Shock and Vibration, 2015 This paper proposes the time-delayed cubic velocity feedback control strategy to improve the isolation performance of High-Static-Low-Dynamic-Stiffness (HSLDS) vibration isolator.
Yong Wang +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Identifying Ordinal Similarities at Different Temporal Scales
EntropyThis study implements the permutation Jensen–Shannon distance as a metric for discerning ordinal patterns and similarities across multiple temporal scales in time series data.
Luciano Zunino +2 more
doaj +1 more source