Results 81 to 90 of about 27,174,491 (303)
Frontiers in Neuroscience, 2018 Alzheimer’s disease (AD) is characterized by progressive deterioration of brain function among elderly people. Studies revealed aberrant correlations in spontaneous blood oxygen level-dependent (BOLD) signals in resting-state functional magnetic ...
Yan Niu +10 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Valuation of Credit Derivatives with Multiple Time Scales in the Intensity Model
, 2014 We propose approximate solutions for pricing zero-coupon defaultable bonds, credit default swap rates, and bond options based on the averaging principle of stochastic differential equations.
김범진, 박찬열
core
An IRT Analysis of Motive Questionnaires: The Unified Motive Scales [PDF]
, 2012 Multiple inventories claiming to assess the same explicit motive (achievement, power, or affiliation) show only mediocre convergent validity. In three studies (N = 1685) the structure, nomological net, and content coverage of multiple existing motive ...
Gerstenberg, Friederike X. R. +1 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Corner Detection Using Multi-directional Structure Tensor with Multiple Scales
, 2020 Corners are important features for image analysis and computer vision tasks. Local structure tensors with multiple scales are widely used in intensity-based corner detectors.
Zhang, W, Sun, C
core +1 more source
Latin American Journal of Solids and StructuresThis paper investigates the dynamic response of rectangular prestressed membrane subjected to concentrated impact load based on multiple scale perturbation method.
Z. L. Zheng, C. Y. Liu, D. Li, T. Zhang
doaj +1 more source
CLASSIFICATION OF INTERNAL RESONANCES IN NONLINEAR FRACTIONALY DAMPED UFLYAND-MINDLIN PLATES
International Journal for Computational Civil and Structural Engineering, 2020 In the present paper, the nonlinear free vibrations of fractionally damped plates are studied, equations of motion of which take the rotary inertia and shear deformations into account and involve fivecoupled nonlinear differentialequations in terms of ...
Marina Shitikova, Elena Osipova
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source