Results 41 to 50 of about 31,893 (252)

A multi-objective genetic algorithm to find active modules in multiplex biological networks.

PLoS Computational Biology, 2021
The identification of subnetworks of interest-or active modules-by integrating biological networks with molecular profiles is a key resource to inform on the processes perturbed in different cellular conditions. We here propose MOGAMUN, a Multi-Objective
Elva María Novoa-Del-Toro, Efrén Mezura-Montes, Matthieu Vignes, Morgane Térézol, Frédérique Magdinier, Laurent Tichit, Anaïs Baudot   +6 more
doaj   +1 more source

Synchronization in delayed multiplex networks [PDF]

EPL (Europhysics Letters), 2015
We study impact of multiplexing on the global phase synchronizability of different layers in the delayed coupled multiplex networks. We find that at strong couplings, the multiplexing induces the global synchronization in sparse networks. The introduction of global synchrony depends on the connection density of the layers being multiplexed, which ...
Singh, A., Ghosh, S., Jalan, S., Kurths, J.   +3 more
openaire   +3 more sources

Optimal Disintegration Strategy in Multiplex Networks under Layer Node-Based Attack

Applied Sciences, 2019
From social networks to complex infrastructures, many systems could be described by multiplex networks formed by a set of nodes connected via more than one type of links. Network disintegration, which is the problem of identifying a set of nodes or edges
Mingze Qi, Yu Bai, Xiaohan Li, Hongzhong Deng, Tao Wang   +4 more
doaj   +1 more source

Similarity matrix average for aggregating multiplex networks

Journal of Physics: Complexity, 2023
We introduce a methodology based on averaging similarity matrices with the aim of integrating the layers of a multiplex network into a single monoplex network.
Federica Baccini, Lucio Barabesi, Eugenio Petrovich   +2 more
doaj   +1 more source

Shortest Paths in Multiplex Networks [PDF]

Scientific Reports, 2017
AbstractThe shortest path problem is one of the most fundamental networks optimization problems. Nowadays, individuals interact in extraordinarily numerous ways through their offline and online life (e.g., co-authorship, co-workership, or retweet relation in Twitter). These interactions have two key features.
Saeed Ghariblou, Mostafa Salehi, Matteo Magnani, Mahdi Jalili   +3 more
openaire   +4 more sources

Cycles and clustering in multiplex networks

Physical Review E, 2016
In multiplex networks, cycles cannot be characterized only by their length, as edges may occur in different layers in different combinations. We define a classification of cycles by the number of edges in each layer and the number of switches between layers.
Baxter, Gareth J., Cellai, Davide, Dorogovtsev, Sergey N., Mendes, José F.F.   +3 more
openaire   +4 more sources

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Functional Integration and Segregation in Multiplex Brain Networks for Alzheimer's Disease

Frontiers in Neuroscience, 2020
Growing evidence links impairment of brain functions in Alzheimer's disease (AD) with disruptions of brain functional connectivity. However, whether the AD brain shows similar changes from a dynamic or cross-frequency view remains poorly explored.
Lihui Cai, Xile Wei, Jing Liu, Lin Zhu, Jiang Wang, Bin Deng, Haitao Yu, Ruofan Wang   +7 more
doaj   +1 more source

Multiplexing in networks and diffusion

Proceedings of the National Academy of Sciences
We study multiplexing—the extent to which people have multiple, distinct types of relationships with the same others. We document empirical multiplexing patterns in Indian village data. We show that relationships such as socializing, advising, helping, and lending are correlated but distinct, while commonly used proxies for networks based on ethnicity ...
Arun G. Chandrasekhar, Vasu Chaudhary, Benjamin Golub, Matthew O. Jackson   +3 more
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source