Results 211 to 220 of about 279,791 (361)

Multiplex-PCR-Based Screening and Computational Modeling of Virulence Factors and T-Cell Mediated Immunity in Helicobacter pylori Infections for Accurate Clinical Diagnosis

, 2015
Sinem Öktem Okullu, Arzu Tiftikçi, Murat Saruç, Bahattin Çıçek, Eser Vardareli, Nurdan Tözün, Tanıl Kocagöz, Osman Uğur Sezerman, Ahmet Sinan Yavuz, Ayca Sayi‐Yazgan   +9 more
openalex   +2 more sources

Adipocyte‐Derived Exosomal miR‐5099 Mitigates M1 Macrophage Polarization and Adipose Inflammation via c‐Met/NF‐κB Axis to Improve Metabolic Health

Advanced Science, EarlyView.
Celastrol upregulates adipocyte‐derived exosomal miR‐5099, suppressing the macrophage c‐Met/NF‐κB axis to mitigate pro‐inflammatory M1 polarization and adipose inflammation. These miR‐5099‐enriched exosomes also act as endocrine signals targeting the liver, muscle, and adipocytes to significantly enhance systemic insulin sensitivity.
Ping Tang, Lixin Tai, Hongxia Xu, Dongliang Zhu, Jiajia Li, Hao Feng, Jinghui Cui, Shuhai Lin, Li‐jun Di, Li Wang   +9 more
wiley   +1 more source

Multiplex PCR assay for the rapid detection of <i>Klebsiella pneumoniae</i> pathotypes. [PDF]

J Med Microbiol
Kulkarni SM, Jacob JJ, Praveen T, Aravind V, Subbulakshmi R, Preethi S, Lal B, Gunasekaran K, Manesh A, Karve SM, Sudarsana J, Bhattacharya S, Shah A, Nagaraj S, Padaki P, Jayakumar S, Mathew R, Rudresh SM, Qureshi S, Nivedhana S, Joe G, Rajni E, Walia K, Veeraraghavan B.   +23 more
europepmc   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Point-Of-Care Respiratory Diagnosis and Antibiotic Utilization in the Emergency Department: A Prospective Evaluation of Multiplex PCR. [PDF]

Acad Emerg Med
Meltzer AC, Payette C, Heidish R, Lagunzad I, Loganathan A, Bolden T, Friedman M, Pieri M, Huang W, DeBritz D, Luck N, Lee SM.   +11 more
europepmc   +1 more source

NK Cell Activation by Platinum Boosts Immunotherapy in HR+/HER2− Breast Cancer

Advanced Science, EarlyView.
Multi‐omics and single‐cell analyses identify activated NK cells as key mediators of anti‐PD‐(L)1 response in HR+/HER2− breast cancer. Platinum chemotherapy enhances NK cell cytotoxicity through NF‐κB–associated signaling, synergizing with immunotherapy and providing a rationale for combination treatment.
Yi‐Yu Chen, Yi‐Fan Zhou, Xuan Qi, Ya‐Xin Zhao, Tong Fu, Xi Jin, Minhong Shen, Yi‐Zhou Jiang, Zhi‐Ming Shao   +8 more
wiley   +1 more source

Clinical evaluation of multiplex PCR for the differential diagnosis of major pathogenic mycobacteria in East China. [PDF]

Medicine (Baltimore)
Fang T, Peng L, Li Z, Li H, Li H, Cai L.
europepmc   +1 more source

Evaluation of Real-Time PCR Coupled With Multiplex Probe Melting Curve Analysis for Pathogen Detection in Patients With Suspected Bloodstream Infections [PDF]

, 2019
Yao Xiao, Xu Shen, Qifeng Zhao, Yihui Yao, Tian‐Ci Yang, Jianjun Niu   +5 more
openalex   +1 more source

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo, Ying Yu, Zhimin Zeng, Yanxin Chen, Yali Yi, Zhiqin Lu, Fujuan Zeng, Peng Xu, Daya Luo, Leifeng Chen, Anwen Liu   +10 more
wiley   +1 more source

Development of a rapid, simple multiplex PCR-dipstick assay for the detection of <i>Neisseria meningitidis</i> serogroups in clinical isolates. [PDF]

Front Cell Infect Microbiol
Matsuba M, Mahazu S, Shimuta K, Ablordey A, Takahashi H, Saito R.   +5 more
europepmc   +1 more source