Results 251 to 260 of about 281,013 (338)

Diagnostic performance of Pneumonia multiplex PCR in critically ill immunocompromised patients. [PDF]

Crit Care
Contier J, Platon L, Benchabane N, Tchakerian S, Herman F, Mollevi C, Ceballos P, Godreuil S, Klouche K.   +8 more
europepmc   +1 more source

Stress‐Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer

Advanced Science, EarlyView.
Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao, Xuliren Wang, Han Zhu, Ling Yao, Qi Zhang, Zihan Zhai, Xinyi Lv, Xinyuan Xia, Yi Zhang, Xinya Lu, Xinyi Quan, Jiawen Yang, Xinwei Li, Jieyi Dong, Zhi‐ming Shao, Ruoxi Wang, Bingqiu Xiu, Jiong Wu, Sheng Chen   +18 more
wiley   +1 more source

RAPID-CARE: Rapid Antibiotic Optimization in the ICU After Implementation of a Pneumonia Multiplex PCR Test-A Real-World Evaluation. [PDF]

Antibiotics (Basel)
Rodríguez-Gómez M, Martínez-Sagasti F, Calle-Romero M, Prieto-Cabrera A, De La Montaña-Díaz P, Díaz-De la Torre I, Delgado-Iribarren García-Campero A, Domingo-Marín S, Sánchez-García M, Martín-Loeches I.   +9 more
europepmc   +1 more source

Plasma‐based analysis of ERBB2 mutational status by multiplex digital PCR in a large series of patients with metastatic breast cancer [PDF]

Julien Corné, Véronique Quillien, Florence Godey, Mathilde Cherel, Agathe Cochet, Fanny Le Du, Lucie Robert, Héloïse Bourien, Angélique Brunot, Laurence Crouzet, Christophe Perrin, Claudia Lefeuvre‐Plesse, Véronique Dièras, Thibault De La Motte Rouge   +13 more
openalex   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source

A multiplex PCR for rapid detection of vancomycin and linezolid resistance genes in clinical and environmental enterococci: A one health diagnostic approach. [PDF]

One Health
Wada Y, Bouafia NA, Al Shammari BR, Afolabi HA, Aljebaly FSM, Almogbel MS, Garout M, Halwani MA, Almansour ZH, Alwashmi ASS, AlKaabi NA, Al-Subaie MF, Rabaan AA, Yean CY, Abdul Rahman Z.   +14 more
europepmc   +1 more source

Multiplex polymerase chain reaction (PCR) method for the rapid and sensitive species-specific detection of the harmful alga, Prymnesium parvum Carter (Haptophyta)

, 2015
Schonna R. Manning
openalex   +1 more source

Dual Targeting of Tau Kinases and Autophagy by Abemaciclib Independent of CDK4/6 Inhibition

Advanced Science, EarlyView.
Abemaciclib rescues cognitive function and attenuates tau pathology in Alzheimer's disease models, but not through its known cancer‐fighting mechanism. This study demonstrates that abemaciclib operates independently of CDK4/6 inhibition, instead directly targeting tau kinases CaMKII and GSK3β while simultaneously promoting autophagic clearance of ...
Jihui Han, June‐Hyun Jeong, Dongjoon Lee, Yujin Jung, Yujin Jin, Eun Sun Jung, Haeng Jun Kim, Woo Youn Kim, Chang‐Han Lee, Inhee Mook‐Jung   +9 more
wiley   +1 more source

A novel species-specific multiplex PCR assay for the differentiation of five Fowl adenovirus species (A to E): Application to field surveillance. [PDF]

Poult Sci
Song H, Kim H, Kim J, Her M, Kim H.
europepmc   +1 more source

The study and identification of Quorum Sensing (QS) genes of Pseudomonas aeruginosa strains isolated from human clinical samples by Multiplex PCR and antibiotic resistance determination

, 2016
Firozeh Amini Bezanjanii, Razegh Mahmoudi, Kiuomars Amini   +2 more
openalex   +1 more source