Results 31 to 40 of about 944,235 (271)

BISMO: A Scalable Bit-Serial Matrix Multiplication Overlay for Reconfigurable Computing

, 2018
Matrix-matrix multiplication is a key computational kernel for numerous applications in science and engineering, with ample parallelism and data locality that lends itself well to high-performance implementations.
Rasnayake, Lahiru, Sjalander, Magnus, Umuroglu, Yaman   +2 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Insights into Tissue-Specific Specialized Metabolism in Wampee (Clausena lansium (Lour.) Skeels) Varieties

Foods
Wampee (Clausena lansium (Lour.) Skeels) has natural bioactive components with diverse health benefits, but its detailed metabolism and tissue distribution are not fully understood.
Ran Zhang, Junjie Zhou, Xiaoxuan Zhang, Huanteng Hou, Xianqing Liu, Chenkun Yang, Shuangqian Shen, Jie Luo   +7 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Construction of an ultrahigh-density genetic linkage map for Manihot esculenta Crantz and identification of QTL for root quantity traits

BMC Plant Biology
Cassava, Manihot esculenta Crantz, is the main raw material used in starch production in China. However, due to the small planting scale and high demand in China, large-scale imports are needed.
Qi Liu, Zixuan Li, Zihao Wang, Yanjie Lu, Sirong Jiang, Chengcai Xia, Pengliang An, Long Zhao, Ke Deng, Zhiqiang Xia, Wenquan Wang   +10 more
doaj   +1 more source

The After-Effect of Organic Fertilizer Varies among Climate Conditions in China: A Meta-Analysis

Agronomy
Organic fertilizer is utilized to improve the organic carbon levels in arable soils, which is helpful for soil quality improvement and crop yield increase.
Shaodong Wang, Yifan Li, Qian Li, Xucan Ku, Guoping Pan, Qiyun Xu, Yao Wang, Yifei Liu, Shuaiwen Zeng, Shah Fahad, Hongyan Liu, Jiaolong Li   +11 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Physiological and Transcriptomic Mechanisms Underlying Vitamin C-Mediated Cold Stress Tolerance in Grafted Cucumber

Plants
Cucumbers (Cucumis sativus L.) are highly sensitive to cold, but grafting onto cold-tolerant rootstocks can enhance their low-temperature resilience.
Panpan Yu, Junkai Wang, Xuyang Zhang, Zhenglong Weng, Kaisen Huo, Qiuxia Yi, Chenxi Wu, Sunjeet Kumar, Hao Gao, Lin Fu, Yanli Chen, Guopeng Zhu   +11 more
doaj   +1 more source

Photo-excited Carrier Dynamics and Impact Excitation Cascade in Graphene

, 2012
Photo-excitation in solids can trigger a cascade in which multiple particle-hole excitations are generated. We analyze the carrier multiplication cascade of impact excitation processes in graphene and show that the number of pair excitations has a strong
Koppens, Frank H. L., Levitov, Leonid S., Song, Justin C. W., Tielrooij, Klaas J.   +3 more
core   +1 more source

A 334$μ$W 0.158mm$^2$ ASIC for Post-Quantum Key-Encapsulation Mechanism Saber with Low-latency Striding Toom-Cook Multiplication Authors Version [PDF]

, 2023
Archisman Ghosh, Jose Maria Bermudo Mera, Angshuman Karmakar, Debayan Das, Santosh Ghosh, Ingrid Verbauwhede, Shreyas Sen   +6 more
openalex   +1 more source