Results 21 to 30 of about 219,162 (314)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Glutathione-gold nanoclusters enhance sweet potato thermotolerance through improved photosynthesis, redox homeostasis, and cellular integrity

BMC Plant Biology
Background Global warming severely challenges sweet potato cultivation by disrupting physiological, biochemical, and structural processes. The potential of glutathione-gold nanoclusters (GSH-Au NCs) in enhancing thermotolerance remains largely unexplored
Sunjeet Kumar, Gurmendar, Rui Yu, Muhammad Ikram, Jingjing Kou, Muhammad Abbas Khan, Mengzhao Wang, Guopeng Zhu   +7 more
doaj   +1 more source

OsUGT88C3 Encodes a UDP-Glycosyltransferase Responsible for Biosynthesis of Malvidin 3-O-Galactoside in Rice

Plants
The diversity of anthocyanins is largely due to the action of glycosyltransferases, which add sugar moieties to anthocyanidins. Although a number of glycosyltransferases have been identified to glycosylate anthocyanidin in plants, the enzyme that ...
Sihan Zhao, Shuying Fu, Zhenfeng Cao, Hao Liu, Sishu Huang, Chun Li, Zhonghui Zhang, Hongbo Yang, Shouchuang Wang, Jie Luo, Tuan Long   +10 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Transmission of areca palm velarivirus 1 (APV1) by Pseudococcus cryptus

Phytopathology Research
Betel palm is one of the most economically important crops in Southeast Asia. The occurrence and expansion of yellow leaf disease (YLD) have significantly impacted betel palm plantations.
Xue Zhao, Ruibai Zhao, Xianmei Cao, Yutian Wang, Hongxing Wang, Xi Huang   +5 more
doaj   +1 more source

Rational Nitrogen Reduction Helps Mitigate the Nitrogen Pollution Risk While Ensuring Rice Growth in a Tropical Rice–Crayfish Coculture System

Agriculture
The incorporation of aquaculture feed within a rice–crayfish coculture system significantly enhances nitrogen cycling, thereby diminishing the reliance on chemical fertilizers.
Yifan Li, Yixian Wu, Shaodong Wang, Hui Peng, Fan Zheng, Guoping Pan, Yifei Liu, Hongyan Liu   +7 more
doaj   +1 more source

Multiple targets for multiple sclerosis

Genes & Diseases, 2015
Multiple sclerosis (MS), a leading cause of non-traumatic disability in young adults, is a chronic inflammatory demyelinating disease of the central nervous system (CNS) associated with aberrant autoimmune responses. It has long been thought that therapeutic development should be centered on immunomodulatory agents.
Hu, Li-Tian, Sun, Fei, Chen, Guo-Jun
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Genomic diversity of Capillovirus uniheveae (Betaflexiviridae) infecting Hevea brasiliensis Muell. Arg. in Hainan, China

BMC Genomics
Background Rubber tree (Hevea brasiliensis Muell. Arg.) is a significant commercial crop in tropical areas worldwide, with rubber production threatened by Tapping Panel Dryness (TPD).
Hao Wang, Ruibai Zhao, Xi Huang, Hongxing Wang, Xianmei Cao   +4 more
doaj   +1 more source

Foliar application of zinc oxide nanoparticles improved yield and 2-acetyl-1-pyrroline content in fragrant rice under salt stress

Crop and Environment
Exogenous application of zinc oxide nanoparticles (ZnO NPs) has been shown to increase the stress resistance of crops, however, its effects on the yield and 2-acetyl-1-pyrroline (2-AP) content of fragrant rice under salt stress remain unclear.
Lin Li, Zheng Huang, Zhenxiang Zhou, Ye Tao, Yicheng Zhang, Yixue Mu, Shu Wu, Lixiao Nie   +7 more
doaj   +1 more source