Results 91 to 100 of about 891,373 (316)

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Complex centers of polynomial differential equations

open access: yesElectronic Journal of Differential Equations, 2007
We present some results on the existence and nonexistence of centers for polynomial first order ordinary differential equations with complex coefficients.
Mohamad Ali M. Alwash
doaj  

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Existence of infinitely solutions for a modified nonlinear Schrodinger equation via dual approach

open access: yesElectronic Journal of Differential Equations, 2018
In this article, we focus on the existence of infinitely many weak solutions for the modified nonlinear Schrodinger equation $$ -\Delta u+V(x) u-[\Delta(1+u^2)^{\alpha/2}]\frac{\alpha u}{2(1+u^2) ^{\frac{2-\alpha}2}}=f(x,u),\quad \text{in } \mathbb{
Xinguang Zhang   +3 more
doaj  

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

open access: yesFEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki   +4 more
wiley   +1 more source

Limits of Localism

open access: yesTransactions of the Association of European Schools of Planning, 2017
A trend in the planning discourse tends to portray the local in a positive light. This paper critically examines localism and regionalism, from a theoretical point of view, to find out whether this positive outlook may be maintained.
Ali Madanipoura
doaj   +1 more source

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

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