Results 91 to 100 of about 892,858 (269)
The images of time in the epoch of multiculturalism
The article is devoted to the comprehension of the connection between the idea and practice of multiculturalism and images of time that define the identity of classical cultural models.
Ina Nalivaika
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This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Multiple solutions for a class of Schrödinger–Bopp–Podolsky system with sublinear nonlinearity
In this paper, we investigate the existence and concentration of solutions for the following Schrödinger–Bopp–Podolsky system with sublinear nonlinearity: \begin{equation*} \begin{cases} -\Delta u +\lambda V(x) u+ G(x)\phi u =f(x,u) & \text{in}~\mathbb ...
Jiexiong Jin, Yingqi Luo, Guofeng Che
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
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Using multiple primary endpoints in clinical trials with a focus on heart failure
The use of multiple primary endpoints in cardiovascular clinical trials could be useful addition to the arsenal of comprehensive evaluations of meaningful clinical outcomes.
Stefan D. Anker +3 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Adoptees Traveling Worlds: Love and Multiplicitous Being in Adoptees’ Autofictional Writing
In the adoptive family, discourses of love have been mobilized to attach the adoptee to the intimate space of the nuclear family, thereby detaching them from other spaces and meaningful others. In this article, I engage with the question of what kinds of
Sophie Withaeckx
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
This article examines the role of plants shaping the political ecology (PE) of the conservation of the Andean páramos in the Sumapaz Region in Colombia.
Camilo Castillo Estupiñan
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PROCESS OSCILLATIVITY STUDY IN APERIODIC CONTINUOUS SYSTEMS, GENERATED BY EIGENVALUES MULTIPLICATION FACTOR [PDF]
The article deals with the steady aperiodic continuous system with state matrix obtaining the spectrum of multiple eigenvalues which multiplicity is equal to dimension of its state vector.
T. A. Akunov +3 more
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