Results 121 to 130 of about 114,760,913 (293)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Control de velocidad, Variables públicas y control de cámara en Unity
, 2018 En este OVA, se continúa con el proceso de implementación del juego Roll-a-Ball. En primer lugar se explica cómo controlar la velocidad de la esfera para que no sea completamente constante.
Jorge Luis Bacca Acosta +1 more
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Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Manchester Unity Building during Coronation week
, 1937 Album 913 includes photographs of Manchester Unity Building, members, meetings, conferences and views of Sydney.
Photographer: Unknown +1 more
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Consideration of Applications for Subvention by Organization of African Trade Union Unity (OATUU) [PDF]
, 1976 Council of Ministers Twenty-Sixth Ordinary Session Addis Ababa- February 1976This is an application request from the Organization of African Trade Union Unity (OATUU) to the General Secretariat of the OAU for its usual subvention to support its ...
Organization of African Unity
core
Draft Financial Rules and Regulations of the Organization of African Unity
, 1978 This report contains the draft financial rules and regulations to be applied to the budget and financial management of the Organization of African Unity and all its ...
Organization of African Unity
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source