Results 101 to 110 of about 5,636 (282)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
New categories for responsible corporate governance starting from the “unity in multiplicity”
Company survival is connected to the integrated picture of company responsibilities, that are deeply involved in network corporate governance. The case analyzed in the work - EoC Spa - highlights the mechanisms which make responsible governance possible,
Baldarelli, Maria-Gabriella +4 more
core +1 more source
This article discusses Hermann Cohen’s philosophy of virtues and presents, on its basis, an idea of the unity of human self-consciouness and God’s oneness.
Reiner Wiehl
doaj
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Presenting architectural content in the work The Tunnel by Magdalena Parys is the purpose of this article. The author analizes the connection beetwen The Tunnel's heores and their surround-ings.
Trygar, Barbara
core
The theme of the article aims at interpreting the artistic creativity of Lidia Sztwiertnia – the sculptress from BielskoBiała – in the context of the philosophy of ‘multiplicity and unity of arts’.
Teresa Rączka
doaj
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Unity in Multiplicity: Towards Working Enterprise Systems
Enterprise systems are attractive exactly as they promise a stronger unity – integration, collaborationand standardization – across distinct and different organisational units of a business. However,empirical research on enterprise systems has documented
Gasparas, Jarulaitis, Monteiro, Eric
core
UNITY IN MULTIPLICITY: ZEHRA ÇOBANLI’S "TULIPS
Türklerin gündelik yaşamında ve kültüründe tabiat ve çiçek sevgisi önemli bir yer tutmaktadır. Bu sevgi geçmişten günümüze farklı alanlardaki Türk sanat dallarına esin kaynağı olabilmektedir.
Kenan, L Mia
core

